DegronMD - Q9Y4X0(AMMECR1)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.A101V	TCGA-A5-A1OF	UCEC	TCGA	PSSSS	DEG_SPOP_SBC_1	108:112	Mutation rewiring degron network	0.1389
p.A101V	DO42568	UCEC	ICGC	PSSSS	DEG_SPOP_SBC_1	108:112	Mutation rewiring degron network	0.1389
p.P119L	TCGA-AX-A2HG	UCEC	TCGA	PSSSS	DEG_SPOP_SBC_1	108:112	Mutation rewiring degron network	0.1389
p.S111L	TCGA-CV-7568	HNSC	TCGA	PSSSS	DEG_SPOP_SBC_1	108:112	Mutation altering degron motif	0.7667
p.S111L	SIDM00239	Kidney Carcinoma	GDSC	PSSSS	DEG_SPOP_SBC_1	108:112	Mutation altering degron motif	0.7667
p.S111L	SIDM00359	Colorectal Carcinoma	GDSC	PSSSS	DEG_SPOP_SBC_1	108:112	Mutation altering degron motif	0.7667
p.S111L	ACH-000159	Kidney Cancer	CCLE	PSSSS	DEG_SPOP_SBC_1	108:112	Mutation altering degron motif	0.7667
p.S111L	ACH-000565	Colon/Colorectal Cancer	CCLE	PSSSS	DEG_SPOP_SBC_1	108:112	Mutation altering degron motif	0.7667
p.S121F	TCGA-EE-A180	SKCM	TCGA	PSSSS	DEG_SPOP_SBC_1	108:112	Mutation rewiring degron network	0.0833
p.S121F	DO47537	SKCM	ICGC	PSSSS	DEG_SPOP_SBC_1	108:112	Mutation rewiring degron network	0.0833
p.P100L	TCGA-QG-A5YW	COAD	TCGA	PSSSS	DEG_SPOP_SBC_1	108:112	Mutation rewiring degron network	0.1111
p.A114T	DO225012	BRCA	ICGC	PSSSS	DEG_SPOP_SBC_1	108:112	Mutation rewiring degron network	0.2778
p.S112C	DO218065	BRCA	ICGC	PSSSS	DEG_SPOP_SBC_1	108:112	Mutation altering degron motif	0.7541
p.W109L	DO218928	LUAD	ICGC	PSSSS	DEG_SPOP_SBC_1	108:112	Mutation altering degron motif	0.7015
p.G120S	DO220851	MELA	ICGC	PSSSS	DEG_SPOP_SBC_1	108:112	Mutation rewiring degron network	0.1111
p.V103F	DO50729	ORCA	ICGC	PSSSS	DEG_SPOP_SBC_1	108:112	Mutation rewiring degron network	0.1944
p.A113V	DO46394	OV	ICGC	PSSSS	DEG_SPOP_SBC_1	108:112	Mutation rewiring degron network	0.3056
p.A102T	DO51154	PRAD	ICGC	PSSSS	DEG_SPOP_SBC_1	108:112	Mutation rewiring degron network	0.1667
p.D102N	DO51257	SKCM	ICGC	PSSSS	DEG_SPOP_SBC_1	108:112	Mutation rewiring degron network	0.1667
p.C104G	DO41572	UCEC	ICGC	PSSSS	DEG_SPOP_SBC_1	108:112	Mutation rewiring degron network	0.2222
p.E119K	DO41572	UCEC	ICGC	PSSSS	DEG_SPOP_SBC_1	108:112	Mutation rewiring degron network	0.1389
p.R117I	DO43907	UCEC	ICGC	PSSSS	DEG_SPOP_SBC_1	108:112	Mutation rewiring degron network	0.1944

Kaplan plot for AMMECR1 in

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons

AMMECR1

UniProt ID: Q9Y4X0

Entrez ID: 9949

Protein name: AMME syndrome candidate gene 1 protein

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for AMMECR1 in