DegronMD - Q9Y5F9(PCDHGB6)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.V893G	TCGA-24-1103	OV	TCGA	DYR	CBL_MET	888:890	Mutation rewiring degron network	0.25
p.V893G	DO28089	OV	ICGC	DYR	CBL_MET	888:890	Mutation rewiring degron network	0.25
p.V886M	TCGA-86-8055	LUAD	TCGA	DYR	CBL_MET	888:890	Mutation rewiring degron network	0.2778
p.V886M	DO25554	LUAD	ICGC	DYR	CBL_MET	888:890	Mutation rewiring degron network	0.2778
p.V886M	SLVL	haematopoietic and lymphoid tissue	COSMIC	DYR	CBL_MET	888:890	Mutation rewiring degron network	0.2778
p.R890C	TCGA-A5-A1OF	UCEC	TCGA	DYR	CBL_MET	888:890	Mutation altering degron motif	0.8301
p.R890C	DO42568	UCEC	ICGC	DYR	CBL_MET	888:890	Mutation altering degron motif	0.8301
p.R890H	TCGA-B5-A3FC	UCEC	TCGA	DYR	CBL_MET	888:890	Mutation altering degron motif	0.8244
p.R890H	DO41871	UCEC	ICGC	DYR	CBL_MET	888:890	Mutation altering degron motif	0.8244
p.P896T	DO233115	GACA	ICGC	DYR	CBL_MET	888:890	Mutation rewiring degron network	0.1667
p.T882A	DO48918	PBCA	ICGC	DYR	CBL_MET	888:890	Mutation rewiring degron network	0.1667

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons