DegronMD - Q9Y6H8(GJA3)

GO - Biological processes (BP): View more >>

GO - Molecular function (MF): View more >>

GO - Cellular component (CC): View more >>

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.A366V	TCGA-BS-A0UV	UCEC	TCGA	VGSSS	DEG_SPOP_SBC_1	355:359	Mutation rewiring degron network	0.1389
p.A366V	DO42793	UCEC	ICGC	VGSSS	DEG_SPOP_SBC_1	355:359	Mutation rewiring degron network	0.1389
p.A363V	DO230346	COCA	ICGC	VGSSS	DEG_SPOP_SBC_1	355:359	Mutation rewiring degron network	0.2222
p.T348M	DO234160	ESAD	ICGC	VGSSS	DEG_SPOP_SBC_1	355:359	Mutation rewiring degron network	0.1389
p.A276T	DO224605	LUSC	ICGC	PPYY	ITCH	269:272	Mutation rewiring degron network	0.2222
p.H364Q	SIDM00117	Non-Small Cell Lung Carcinoma	GDSC	VGSSS	DEG_SPOP_SBC_1	355:359	Mutation rewiring degron network	0.1944
p.H364Q	ACH-000837	Lung Cancer	CCLE	VGSSS	DEG_SPOP_SBC_1	355:359	Mutation rewiring degron network	0.1944
p.E367K	ACH-000934	Breast Cancer	CCLE	VGSSS	DEG_SPOP_SBC_1	355:359	Mutation rewiring degron network	0.1111

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons