DegronMD - Q9Y6Q2(STON1)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.S110L	DO51894	BLCA	ICGC	PESSS	DEG_SPOP_SBC_1	106:110	Mutation altering degron motif	0.7667
p.S110L	DO219009	BLCA	ICGC	PESSS	DEG_SPOP_SBC_1	106:110	Mutation altering degron motif	0.7667
p.S110L	DO233193	GACA	ICGC	PESSS	DEG_SPOP_SBC_1	106:110	Mutation altering degron motif	0.7667
p.P113L	DO6064	BRCA	ICGC	PESSS	DEG_SPOP_SBC_1	106:110	Mutation rewiring degron network	0.25
p.T99I	DO9322	COAD	ICGC	PESSS	DEG_SPOP_SBC_1	106:110	Mutation rewiring degron network	0.1389
p.H100N	DO234415	ESAD	ICGC	PESSS	DEG_SPOP_SBC_1	106:110	Mutation rewiring degron network	0.1667
p.I105S	DO228429	MALY	ICGC	PESSS	DEG_SPOP_SBC_1	106:110	Mutation rewiring degron network	0.3056
p.G118E	DO222434	MELA	ICGC	PESSS	DEG_SPOP_SBC_1	106:110	Mutation rewiring degron network	0.1111
p.E120D	DO222908	MELA	ICGC	PESSS	DEG_SPOP_SBC_1	106:110	Mutation rewiring degron network	0.0556
p.A115T	DO29046	OV	ICGC	PESSS	DEG_SPOP_SBC_1	106:110	Mutation rewiring degron network	0.1944
p.A115T	EoL-1-cell	haematopoietic and lymphoid tissue	COSMIC	PESSS	DEG_SPOP_SBC_1	106:110	Mutation rewiring degron network	0.1944
p.G98R	DO232224	PBCA	ICGC	PESSS	DEG_SPOP_SBC_1	106:110	Mutation rewiring degron network	0.1111
p.I116T	DO42344	UCEC	ICGC	PESSS	DEG_SPOP_SBC_1	106:110	Mutation rewiring degron network	0.1667
p.V101M	ACH-000760	Brain Cancer	CCLE	PESSS	DEG_SPOP_SBC_1	106:110	Mutation rewiring degron network	0.1944
p.V101M	ACH-002269	Brain Cancer	CCLE	PESSS	DEG_SPOP_SBC_1	106:110	Mutation rewiring degron network	0.1944
p.V101M	LNZTA3WT4	central nervous system	COSMIC	PESSS	DEG_SPOP_SBC_1	106:110	Mutation rewiring degron network	0.1944

Kaplan plot for STON1 in

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons

STON1

UniProt ID: Q9Y6Q2

Entrez ID: 11037

Protein name: Stonin-1 (Stoned B-like factor)

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for STON1 in