DegronMD - Q9Y6W3(CAPN7)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.P621Q	TCGA-05-4396	LUAD	TCGA	PPPY	ITCH	624:627	Mutation rewiring degron network	0.25
p.P621Q	TCGA-09-2044	OV	TCGA	PPPY	ITCH	624:627	Mutation rewiring degron network	0.25
p.P621Q	TCGA-DZ-6132	KIRP	TCGA	PPPY	ITCH	624:627	Mutation rewiring degron network	0.25
p.P621Q	DO20919	KIRP	ICGC	PPPY	ITCH	624:627	Mutation rewiring degron network	0.25
p.P621Q	DO23838	LUAD	ICGC	PPPY	ITCH	624:627	Mutation rewiring degron network	0.25
p.P621Q	DO28923	OV	ICGC	PPPY	ITCH	624:627	Mutation rewiring degron network	0.25
p.F769Y	TCGA-A3-3385	KIRC	TCGA	DYR	CBL_MET	764:766	Mutation rewiring degron network	0.25
p.F769Y	DO18532	KIRC	ICGC	DYR	CBL_MET	764:766	Mutation rewiring degron network	0.25
p.S761Y	TCGA-D1-A103	UCEC	TCGA	DYR	CBL_MET	764:766	Mutation rewiring degron network	0.25
p.S761Y	DO42312	UCEC	ICGC	DYR	CBL_MET	764:766	Mutation rewiring degron network	0.25
p.L772V	DO234261	ESAD	ICGC	DYR	CBL_MET	764:766	Mutation rewiring degron network	0.1667
p.L758Q	SIDM00845	Burkitt's Lymphoma	GDSC	DYR	CBL_MET	764:766	Mutation rewiring degron network	0.1667
p.H637Y	SIDM00164	Biliary Tract Carcinoma	GDSC	PPPY	ITCH	624:627	Mutation rewiring degron network	0.0556
p.H637Y	ACH-000209	Bile Duct Cancer	CCLE	PPPY	ITCH	624:627	Mutation rewiring degron network	0.0556

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons