P00519
(LAFTPLDT)
Drug: Nilotinib
Cancer code: STAD
Cancer type: stomach
Drug treatment table
| Degron |
Position |
Sample |
Mutation |
IC50(uM) |
| LAFTPLDT | 646..653 | SIDM00393 | p.T243I | 14.7574 |
| LAFTPLDT | 646..653 | SIDM00393 | p.T243I | 22.995 |
| LAFTPLDT | 646..653 | SIDM00251 | p.G720S | 9.9916 |
| LAFTPLDT | 646..653 | SIDM00251 | p.G720S | 42.713 |
| LAFTPLDT | 646..653 | SIDM00251 | p.E890K | 9.9916 |
| LAFTPLDT | 646..653 | SIDM00251 | p.E890K | 42.713 |
| LAFTPLDT | 646..653 | SIDM00602 | p.P681L | 12.5319 |
| LAFTPLDT | 646..653 | SIDM00602 | p.P681L | 74.547 |
| LAFTPLDT | 646..653 | SIDM01092 | p.R649H | 12.664 |
| LAFTPLDT | 646..653 | SIDM01092 | p.R649H | 46.883 |
