DegronMD: protein-targeted degradation, mutation and drug response to degrons
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BSML
CPH
CGC
P00533
(PLTPSGE)
Drug:
Afatinib
Cancer code:
BRCA
Cancer type:
breast
Drug treatment table
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Degron
Position
Sample
Mutation
IC50(uM)
PLTPSGE
691..697
SIDM00146
p.L469W
4.8192
PLTPSGE
691..697
SIDM00146
p.L469W
54.4963
PLTPSGE
691..697
SIDM00146
p.L469W
5.3557
PLTPSGE
691..697
SIDM00529
p.S703F
1.48
PLTPSGE
691..697
SIDM00529
p.S703F
52.864
PLTPSGE
691..697
SIDM00529
p.S703F
44.302
PLTPSGE
691..697
SIDM00893
p.G182V
0.6557
PLTPSGE
691..697
SIDM00893
p.G182V
19.0787
PLTPSGE
691..697
SIDM00893
p.G182V
14.632
PLTPSGE
691..697
SIDM01042
p.E711K
2.1504
PLTPSGE
691..697
SIDM01042
p.E711K
89.052
PLTPSGE
691..697
SIDM01042
p.E711K
6.7133
PLTPSGE
691..697
SIDM00628
p.S703F
0.333
PLTPSGE
691..697
SIDM00628
p.S703F
7.9408
PLTPSGE
691..697
SIDM00628
p.S703F
1.9705
PLTPSGE
691..697
SIDM00528
p.T678M
1.5259
PLTPSGE
691..697
SIDM00528
p.T678M
6.6446
PLTPSGE
691..697
SIDM00528
p.T678M
2.8554
Showing 1 to 18 of 18 entries
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