P04637
(PLSSS)
Drug: MIRA-1
Cancer code: ESCA
Cancer type: oesophagus
Drug treatment table
| Degron |
Position |
Sample |
Mutation |
IC50(uM) |
| PLSSS | 92..96 | SIDM01024 | p.K120N | 809.31 |
| PLSSS | 92..96 | SIDM01031 | p.R248Q | 179.87 |
| PLSSS | 92..96 | SIDM00538 | p.R175H | 477.76 |
| PLSSS | 92..96 | SIDM01032 | p.H193R | 213 |
| PLSSS | 92..96 | SIDM00550 | p.K101* | 244.08 |
| PLSSS | 92..96 | SIDM00956 | p.R248W | 909.12 |
| PLSSS | 92..96 | SIDM00250 | p.G245C | 163.51 |
| PLSSS | 92..96 | SIDM00326 | p.M237I | 217.3 |
| PLSSS | 92..96 | SIDM01030 | p.I195T | 209.03 |
| PLSSS | 92..96 | SIDM00444 | p.T55fs*68 | 163.57 |
| PLSSS | 92..96 | SIDM00551 | p.R248W | 102.18 |
| PLSSS | 92..96 | SIDM00483 | p.Q100* | 1471.3 |
| PLSSS | 92..96 | SIDM00347 | p.V272L | 362.04 |
| PLSSS | 92..96 | SIDM01028 | p.R337C | 986.94 |
| PLSSS | 92..96 | SIDM00369 | p.V272M | 388.65 |
| PLSSS | 92..96 | SIDM00325 | p.N268fs*77 | 183.92 |
| PLSSS | 92..96 | SIDM00530 | p.P152L | 265.9 |
| PLSSS | 92..96 | SIDM00478 | p.S90fs*33 | 330.71 |
| PLSSS | 92..96 | SIDM00477 | p.C135Y | 347.66 |
| PLSSS | 92..96 | SIDM01024 | p.I251fs*13 | 809.31 |
| PLSSS | 92..96 | SIDM00322 | p.E258* | 150.13 |
| PLSSS | 92..96 | SIDM00322 | p.H214R | 150.13 |
| PLSSS | 92..96 | SIDM00479 | p.N310fs*27 | 421.31 |
| PLSSS | 92..96 | SIDM01041 | p.C277F | 197.69 |
| PLSSS | 92..96 | SIDM00328 | p.R248Q | 421.5 |
| PLSSS | 92..96 | SIDM00445 | p.Q192* | 200.61 |
| PLSSS | 92..96 | SIDM00444 | p.R248Q | 163.57 |
| PLSSS | 92..96 | SIDM00539 | p.R248W | 250.41 |
| PLSSS | 92..96 | SIDM01027 | p.E339* | 314.8 |
| PLSSS | 92..96 | SIDM01027 | p.H179R | 314.8 |
| PLSSS | 92..96 | SIDM00278 | p.R273L | 219.21 |
| PLSSS | 92..96 | SIDM00278 | p.Y234C | 219.21 |