P04637
(PLSSS)
Drug: MIRA-1
Cancer code: HNSC
Cancer type: head_and_neck
Drug treatment table
| Degron |
Position |
Sample |
Mutation |
IC50(uM) |
| PLSSS | 92..96 | SIDM00592 | p.G266R | 139.56 |
| PLSSS | 92..96 | SIDM00588 | p.R248Q | 222.86 |
| PLSSS | 92..96 | SIDM00351 | p.E336* | 60.58 |
| PLSSS | 92..96 | SIDM00831 | p.R175H | 167.88 |
| PLSSS | 92..96 | SIDM00937 | p.H193L | 231.66 |
| PLSSS | 92..96 | SIDM00350 | p.E271* | 390.63 |
| PLSSS | 92..96 | SIDM00350 | p.R110L | 390.63 |
| PLSSS | 92..96 | SIDM00565 | p.R249S | 543.37 |
| PLSSS | 92..96 | SIDM00489 | p.R248W | 185.6 |
| PLSSS | 92..96 | SIDM00044 | p.P153fs*28 | 434.72 |
| PLSSS | 92..96 | SIDM00182 | p.H179R | 616.39 |
| PLSSS | 92..96 | SIDM00589 | p.R306fs*1 | 217.41 |
| PLSSS | 92..96 | SIDM00501 | p.P177L | 591.05 |
| PLSSS | 92..96 | SIDM00501 | p.C176F | 591.05 |
| PLSSS | 92..96 | SIDM00501 | p.Q38* | 591.05 |
| PLSSS | 92..96 | SIDM00375 | p.G154V | 305.02 |
| PLSSS | 92..96 | SIDM00375 | p.S106R | 305.02 |
| PLSSS | 92..96 | SIDM01080 | p.C275fs*20 | 255.81 |
| PLSSS | 92..96 | SIDM00591 | p.G293fs*13 | 198.32 |
| PLSSS | 92..96 | SIDM00485 | p.F109fs*37 | 133.28 |
| PLSSS | 92..96 | SIDM00127 | p.S99fs*24 | 779.44 |
| PLSSS | 92..96 | SIDM01081 | p.P151S | 200.87 |
| PLSSS | 92..96 | SIDM00942 | p.R175H | 242.38 |
| PLSSS | 92..96 | SIDM00860 | p.R248L | 240.82 |
| PLSSS | 92..96 | SIDM00485 | p.A307V | 133.28 |
| PLSSS | 92..96 | SIDM00540 | p.L188_P191delLAPP | 101.97 |
