P08581
(DYR)
Drug: Crizotinib
Cancer code: SCLC
Cancer type: lung_small_cell_carcinoma
Drug treatment table
| Degron |
Position |
Sample |
Mutation |
IC50(uM) |
| DYR | 1002..1004 | SIDM00523 | p.L905_H906delinsY | 106.09 |
| DYR | 1002..1004 | SIDM01121 | p.R988C | 23.4821 |
| DYR | 1002..1004 | SIDM00522 | p.V910F | 10.725 |
| DYR | 1002..1004 | SIDM01071 | p.N375S | 19.9725 |
| DYR | 1002..1004 | SIDM00741 | p.S323G | 18.617 |
| DYR | 1002..1004 | SIDM00741 | p.S323G | 11.832 |
| DYR | 1002..1004 | SIDM00245 | p.R1040Q | 10.0853 |
| DYR | 1002..1004 | SIDM00245 | p.R1040Q | 21.337 |
| DYR | 1002..1004 | SIDM00653 | p.T1010I | 20.9555 |
| DYR | 1002..1004 | SIDM00653 | p.T1010I | 50.258 |
| DYR | 1002..1004 | SIDM00927 | p.A204fs*3 | 13.6056 |
