P09874
(VAATPPPS)
Drug: Olaparib
Cancer code: COREAD
Cancer type: large_intestine
Drug treatment table
| Degron |
Position |
Sample |
Mutation |
IC50(uM) |
| VAATPPPS | 365..372 | SIDM00214 | p.S507fs*17 | 51.806 |
| VAATPPPS | 365..372 | SIDM00214 | p.S507fs*17 | 18.7439 |
| VAATPPPS | 365..372 | SIDM00214 | p.S507fs*17 | 40.03 |
| VAATPPPS | 365..372 | SIDM00214 | p.M604I | 51.806 |
| VAATPPPS | 365..372 | SIDM00214 | p.M604I | 18.7439 |
| VAATPPPS | 365..372 | SIDM00214 | p.M604I | 40.03 |
| VAATPPPS | 365..372 | SIDM01090 | p.T910A | 27.6421 |
| VAATPPPS | 365..372 | SIDM01090 | p.T910A | 46.1995 |
| VAATPPPS | 365..372 | SIDM01090 | p.T910A | 118.27 |
| VAATPPPS | 365..372 | SIDM00945 | p.E297* | 144.1141 |
| VAATPPPS | 365..372 | SIDM00945 | p.E297* | 206.5212 |
| VAATPPPS | 365..372 | SIDM00945 | p.E297* | 57.699 |
| VAATPPPS | 365..372 | SIDM00217 | p.I585V | 146.0198 |
| VAATPPPS | 365..372 | SIDM00217 | p.I585V | 192.55 |
| VAATPPPS | 365..372 | SIDM00217 | p.G565R | 146.0198 |
| VAATPPPS | 365..372 | SIDM00217 | p.G565R | 192.55 |
| VAATPPPS | 365..372 | SIDM00217 | p.S507N | 146.0198 |
| VAATPPPS | 365..372 | SIDM00217 | p.S507N | 192.55 |
| VAATPPPS | 365..372 | SIDM00282 | p.K230N | 129.7192 |
| VAATPPPS | 365..372 | SIDM00282 | p.K230N | 254.0929 |
| VAATPPPS | 365..372 | SIDM00282 | p.K230N | 184.75 |
| VAATPPPS | 365..372 | SIDM00150 | p.E602Q | 83.2592 |
| VAATPPPS | 365..372 | SIDM00150 | p.E602Q | 136.3961 |
| VAATPPPS | 365..372 | SIDM00150 | p.E602Q | 86.73 |
| VAATPPPS | 365..372 | SIDM01090 | p.K418fs*2 | 27.6421 |
| VAATPPPS | 365..372 | SIDM01090 | p.K418fs*2 | 46.1995 |
| VAATPPPS | 365..372 | SIDM01090 | p.K418fs*2 | 118.27 |
| VAATPPPS | 365..372 | SIDM00487 | p.E840A | 67.5525 |
| VAATPPPS | 365..372 | SIDM00487 | p.E840A | 32.4328 |
| VAATPPPS | 365..372 | SIDM00487 | p.E840A | 121.5 |
| VAATPPPS | 365..372 | SIDM00217 | p.P359fs*22 | 146.0198 |
| VAATPPPS | 365..372 | SIDM00217 | p.P359fs*22 | 192.55 |
| VAATPPPS | 365..372 | SIDM00837 | p.N440S | 58.7209 |
| VAATPPPS | 365..372 | SIDM00837 | p.N440S | 47.9735 |
| VAATPPPS | 365..372 | SIDM00837 | p.N440S | 86.05 |