P09874
(VAATPPPS)
Drug: Talazoparib
Cancer code: COREAD
Cancer type: large_intestine
Drug treatment table
| Degron |
Position |
Sample |
Mutation |
IC50(uM) |
| VAATPPPS | 365..372 | SIDM00214 | p.S507fs*17 | 2.8201 |
| VAATPPPS | 365..372 | SIDM00214 | p.S507fs*17 | 10.383 |
| VAATPPPS | 365..372 | SIDM00214 | p.M604I | 2.8201 |
| VAATPPPS | 365..372 | SIDM00214 | p.M604I | 10.383 |
| VAATPPPS | 365..372 | SIDM01090 | p.T910A | 5.0437 |
| VAATPPPS | 365..372 | SIDM01090 | p.T910A | 45.622 |
| VAATPPPS | 365..372 | SIDM00945 | p.E297* | 104.3563 |
| VAATPPPS | 365..372 | SIDM00217 | p.I585V | 219.8695 |
| VAATPPPS | 365..372 | SIDM00217 | p.G565R | 219.8695 |
| VAATPPPS | 365..372 | SIDM00217 | p.S507N | 219.8695 |
| VAATPPPS | 365..372 | SIDM00282 | p.K230N | 65.4633 |
| VAATPPPS | 365..372 | SIDM00282 | p.K230N | 19.058 |
| VAATPPPS | 365..372 | SIDM00150 | p.E602Q | 6.3291 |
| VAATPPPS | 365..372 | SIDM00150 | p.E602Q | 11.992 |
| VAATPPPS | 365..372 | SIDM01090 | p.K418fs*2 | 5.0437 |
| VAATPPPS | 365..372 | SIDM01090 | p.K418fs*2 | 45.622 |
| VAATPPPS | 365..372 | SIDM00487 | p.E840A | 14.4677 |
| VAATPPPS | 365..372 | SIDM00487 | p.E840A | 23.157 |
| VAATPPPS | 365..372 | SIDM00217 | p.P359fs*22 | 219.8695 |
| VAATPPPS | 365..372 | SIDM00837 | p.N440S | 1.4584 |
| VAATPPPS | 365..372 | SIDM00837 | p.N440S | 4.9819 |
