P11387
(SKDAKVPSP)
Drug: Irinotecan
Cancer code: COREAD
Cancer type: large_intestine
Drug treatment table
| Degron |
Position |
Sample |
Mutation |
IC50(uM) |
| SKDAKVPSP | 387..395 | SIDM00781 | p.I714T | 149.51 |
| SKDAKVPSP | 387..395 | SIDM00217 | p.R405W | 182.69 |
| SKDAKVPSP | 387..395 | SIDM00217 | p.Y426C | 182.69 |
| SKDAKVPSP | 387..395 | SIDM00217 | p.R434Q | 182.69 |
| SKDAKVPSP | 387..395 | SIDM00217 | p.E517K | 182.69 |
| SKDAKVPSP | 387..395 | SIDM00282 | p.F279L | 15.104 |
| SKDAKVPSP | 387..395 | SIDM00789 | p.M675I | 13.563 |
| SKDAKVPSP | 387..395 | SIDM00789 | p.D760G | 13.563 |
| SKDAKVPSP | 387..395 | SIDM00534 | p.D156Y | 101.22 |
| SKDAKVPSP | 387..395 | SIDM00217 | p.P176fs*4 | 182.69 |
| SKDAKVPSP | 387..395 | SIDM00541 | p.D182A | 78.252 |
| SKDAKVPSP | 387..395 | SIDM00837 | p.W754C | 2.8556 |
| SKDAKVPSP | 387..395 | SIDM00193 | p.K59N | 73.12 |
| SKDAKVPSP | 387..395 | SIDM00193 | p.R89Q | 73.12 |
| SKDAKVPSP | 387..395 | SIDM00193 | p.K150N | 73.12 |
