P11387
(SKDAKVPSP)
Drug: SN-38
Cancer code: COREAD
Cancer type: large_intestine
Drug treatment table
| Degron |
Position |
Sample |
Mutation |
IC50(uM) |
| SKDAKVPSP | 387..395 | SIDM00781 | p.I714T | 0.0892 |
| SKDAKVPSP | 387..395 | SIDM00781 | p.I714T | 0.02 |
| SKDAKVPSP | 387..395 | SIDM00217 | p.R405W | 0.008 |
| SKDAKVPSP | 387..395 | SIDM00217 | p.R405W | 1.1601 |
| SKDAKVPSP | 387..395 | SIDM00217 | p.Y426C | 0.008 |
| SKDAKVPSP | 387..395 | SIDM00217 | p.Y426C | 1.1601 |
| SKDAKVPSP | 387..395 | SIDM00217 | p.R434Q | 0.008 |
| SKDAKVPSP | 387..395 | SIDM00217 | p.R434Q | 1.1601 |
| SKDAKVPSP | 387..395 | SIDM00217 | p.E517K | 0.008 |
| SKDAKVPSP | 387..395 | SIDM00217 | p.E517K | 1.1601 |
| SKDAKVPSP | 387..395 | SIDM00282 | p.F279L | 0.0755 |
| SKDAKVPSP | 387..395 | SIDM00282 | p.F279L | 0.0319 |
| SKDAKVPSP | 387..395 | SIDM00789 | p.M675I | 0.0398 |
| SKDAKVPSP | 387..395 | SIDM00789 | p.M675I | 0.0286 |
| SKDAKVPSP | 387..395 | SIDM00789 | p.D760G | 0.0398 |
| SKDAKVPSP | 387..395 | SIDM00789 | p.D760G | 0.0286 |
| SKDAKVPSP | 387..395 | SIDM00534 | p.D156Y | 0.0211 |
| SKDAKVPSP | 387..395 | SIDM00534 | p.D156Y | 0.0945 |
| SKDAKVPSP | 387..395 | SIDM00217 | p.P176fs*4 | 0.008 |
| SKDAKVPSP | 387..395 | SIDM00217 | p.P176fs*4 | 1.1601 |
| SKDAKVPSP | 387..395 | SIDM00541 | p.D182A | 0.154 |
| SKDAKVPSP | 387..395 | SIDM00541 | p.D182A | 0.1784 |
| SKDAKVPSP | 387..395 | SIDM00837 | p.W754C | 0.0039 |
| SKDAKVPSP | 387..395 | SIDM00837 | p.W754C | 0.0037 |
| SKDAKVPSP | 387..395 | SIDM00193 | p.K59N | 0.0805 |
| SKDAKVPSP | 387..395 | SIDM00193 | p.K59N | 0.0245 |
| SKDAKVPSP | 387..395 | SIDM00193 | p.R89Q | 0.0805 |
| SKDAKVPSP | 387..395 | SIDM00193 | p.R89Q | 0.0245 |
| SKDAKVPSP | 387..395 | SIDM00193 | p.K150N | 0.0805 |
| SKDAKVPSP | 387..395 | SIDM00193 | p.K150N | 0.0245 |