P15056
(LSATPPAS)
Drug: PLX-4720
Cancer code: COREAD
Cancer type: large_intestine
Drug treatment table
| Degron |
Position |
Sample |
Mutation |
IC50(uM) |
| LSATPPAS | 398..405 | SIDM00826 | p.V600E | 0.1948 |
| LSATPPAS | 398..405 | SIDM00826 | p.V600E | 2.8929 |
| LSATPPAS | 398..405 | SIDM00826 | p.V600E | 1.8882 |
| LSATPPAS | 398..405 | SIDM00527 | p.V600E | 11.1863 |
| LSATPPAS | 398..405 | SIDM00527 | p.V600E | 6.7105 |
| LSATPPAS | 398..405 | SIDM00527 | p.V600E | 8.8807 |
| LSATPPAS | 398..405 | SIDM00527 | p.V600M | 11.1863 |
| LSATPPAS | 398..405 | SIDM00527 | p.V600M | 6.7105 |
| LSATPPAS | 398..405 | SIDM00527 | p.V600M | 8.8807 |
| LSATPPAS | 398..405 | SIDM00677 | p.E204* | 239.1703 |
| LSATPPAS | 398..405 | SIDM00677 | p.E204* | 132.5968 |
| LSATPPAS | 398..405 | SIDM00677 | p.E204* | 136.47 |
| LSATPPAS | 398..405 | SIDM01090 | p.V600E | 45.6741 |
| LSATPPAS | 398..405 | SIDM01090 | p.V600E | 28.6275 |
| LSATPPAS | 398..405 | SIDM01090 | p.V600E | 18.61 |
| LSATPPAS | 398..405 | SIDM00945 | p.V600E | 2.766 |
| LSATPPAS | 398..405 | SIDM00945 | p.V600E | 5.252 |
| LSATPPAS | 398..405 | SIDM00945 | p.V600E | 47.052 |
| LSATPPAS | 398..405 | SIDM00498 | p.V600E | 19.3586 |
| LSATPPAS | 398..405 | SIDM00498 | p.V600E | 13.5538 |
| LSATPPAS | 398..405 | SIDM00498 | p.V600E | 21.224 |
| LSATPPAS | 398..405 | SIDM00812 | p.V600E | 27.9632 |
| LSATPPAS | 398..405 | SIDM00812 | p.V600E | 60.9245 |
| LSATPPAS | 398..405 | SIDM00812 | p.V600E | 45.522 |
| LSATPPAS | 398..405 | SIDM00660 | p.V600E | 7.6466 |
| LSATPPAS | 398..405 | SIDM00660 | p.V600E | 7.7144 |
| LSATPPAS | 398..405 | SIDM00660 | p.V600E | 7.57 |
| LSATPPAS | 398..405 | SIDM00150 | p.A404fs*9 | 152.3118 |
| LSATPPAS | 398..405 | SIDM00150 | p.A404fs*9 | 147.618 |
| LSATPPAS | 398..405 | SIDM00150 | p.A404fs*9 | 195.01 |
| LSATPPAS | 398..405 | SIDM00136 | p.V600E | 4.7456 |
| LSATPPAS | 398..405 | SIDM00136 | p.V600E | 6.9569 |
| LSATPPAS | 398..405 | SIDM00136 | p.V600E | 7.1667 |
| LSATPPAS | 398..405 | SIDM00541 | p.N581Y | 167.3606 |
| LSATPPAS | 398..405 | SIDM00541 | p.N581Y | 34.291 |
| LSATPPAS | 398..405 | SIDM00680 | p.D211G | 35.2742 |
| LSATPPAS | 398..405 | SIDM00680 | p.D211G | 217.5603 |
| LSATPPAS | 398..405 | SIDM00680 | p.D211G | 413.5 |
| LSATPPAS | 398..405 | SIDM00777 | p.G596R | 18.9574 |
| LSATPPAS | 398..405 | SIDM00777 | p.G596R | 172.243 |
| LSATPPAS | 398..405 | SIDM00677 | p.E204V | 239.1703 |
| LSATPPAS | 398..405 | SIDM00677 | p.E204V | 132.5968 |
| LSATPPAS | 398..405 | SIDM00677 | p.E204V | 136.47 |
| LSATPPAS | 398..405 | SIDM00214 | p.R726C | 188.8846 |
| LSATPPAS | 398..405 | SIDM00214 | p.R726C | 134.821 |
| LSATPPAS | 398..405 | SIDM00214 | p.R726C | 269.92 |
| LSATPPAS | 398..405 | SIDM00217 | p.V120I | 173.5516 |
| LSATPPAS | 398..405 | SIDM00217 | p.V120I | 334.77 |
| LSATPPAS | 398..405 | SIDM00217 | p.S76P | 173.5516 |
| LSATPPAS | 398..405 | SIDM00217 | p.S76P | 334.77 |
| LSATPPAS | 398..405 | SIDM00150 | p.A712T | 152.3118 |
| LSATPPAS | 398..405 | SIDM00150 | p.A712T | 147.618 |
| LSATPPAS | 398..405 | SIDM00150 | p.A712T | 195.01 |
| LSATPPAS | 398..405 | SIDM00534 | p.R354Q | 178.9034 |
| LSATPPAS | 398..405 | SIDM00534 | p.R354Q | 121.4102 |
| LSATPPAS | 398..405 | SIDM00534 | p.R354Q | 102.35 |
| LSATPPAS | 398..405 | SIDM00487 | p.R506G | 140.6543 |
| LSATPPAS | 398..405 | SIDM00487 | p.R506G | 143.2376 |
| LSATPPAS | 398..405 | SIDM00487 | p.R506G | 117.58 |
| LSATPPAS | 398..405 | SIDM00487 | p.S273N | 140.6543 |
| LSATPPAS | 398..405 | SIDM00487 | p.S273N | 143.2376 |
| LSATPPAS | 398..405 | SIDM00487 | p.S273N | 117.58 |
| LSATPPAS | 398..405 | SIDM00136 | p.T119S | 4.7456 |
| LSATPPAS | 398..405 | SIDM00136 | p.T119S | 6.9569 |
| LSATPPAS | 398..405 | SIDM00136 | p.T119S | 7.1667 |
| LSATPPAS | 398..405 | SIDM00537 | p.T529A | 44.089 |
| LSATPPAS | 398..405 | SIDM00537 | p.T529A | 89.9366 |
| LSATPPAS | 398..405 | SIDM00537 | p.T529A | 69.682 |