P53350
(NRKPLTVLN)
Drug: MK-1775
Cancer code: COREAD
Cancer type: large_intestine
Drug treatment table
| Degron |
Position |
Sample |
Mutation |
IC50(uM) |
| NRKPLTVLN | 336..344 | SIDM00826 | p.K601N | 1.3839 |
| NRKPLTVLN | 336..344 | SIDM00214 | p.R354H | 1.4325 |
| NRKPLTVLN | 336..344 | SIDM00217 | p.R441C | 1.0304 |
| NRKPLTVLN | 336..344 | SIDM01096 | p.Q283* | 0.6997 |
| NRKPLTVLN | 336..344 | SIDM00150 | p.S375G | 0.413 |
| NRKPLTVLN | 336..344 | SIDM00660 | p.P151S | 0.6095 |
| NRKPLTVLN | 336..344 | SIDM00660 | p.R500H | 0.6095 |
| NRKPLTVLN | 336..344 | SIDM00487 | p.V587delV | 0.4067 |
| NRKPLTVLN | 336..344 | SIDM00537 | p.G238W | 0.7137 |
