Q15059
(PATPFQS)
Drug: OTX015
Cancer code: COREAD
Cancer type: large_intestine
Drug treatment table
| Degron |
Position |
Sample |
Mutation |
IC50(uM) |
| PATPFQS | 179..185 | SIDM00498 | p.P24fs*24 | 11.312 |
| PATPFQS | 179..185 | SIDM00945 | p.E25fs*51 | 8.2232 |
| PATPFQS | 179..185 | SIDM00837 | p.P24fs*24 | 3.6348 |
| PATPFQS | 179..185 | SIDM00781 | p.P24fs*51 | 3.8966 |
| PATPFQS | 179..185 | SIDM00781 | p.V190I | 3.8966 |
| PATPFQS | 179..185 | SIDM00537 | p.A216fs*47 | 16.542 |
| PATPFQS | 179..185 | SIDM00537 | p.P24fs*24 | 16.542 |
| PATPFQS | 179..185 | SIDM00783 | p.E25fs*51 | 7.6012 |
| PATPFQS | 179..185 | SIDM00217 | p.R34H | 13.116 |
| PATPFQS | 179..185 | SIDM00282 | p.E564G | 20.069 |
| PATPFQS | 179..185 | SIDM00282 | p.W96* | 20.069 |
| PATPFQS | 179..185 | SIDM00660 | p.P24fs*24 | 7.248 |
| PATPFQS | 179..185 | SIDM00660 | p.E25fs*24 | 7.248 |
| PATPFQS | 179..185 | SIDM00789 | p.P299S | 1.163 |
| PATPFQS | 179..185 | SIDM00534 | p.A172V | 33.596 |
| PATPFQS | 179..185 | SIDM00534 | p.N37K | 33.596 |
| PATPFQS | 179..185 | SIDM00534 | p.V26G | 33.596 |
| PATPFQS | 179..185 | SIDM00680 | p.E25fs*51 | 32.631 |
| PATPFQS | 179..185 | SIDM00487 | p.P24fs*24 | 3.2362 |
| PATPFQS | 179..185 | SIDM00487 | p.E25fs*51 | 3.2362 |
| PATPFQS | 179..185 | SIDM00282 | p.P24fs*24 | 20.069 |
| PATPFQS | 179..185 | SIDM00136 | p.P149A | 1.2126 |
| PATPFQS | 179..185 | SIDM00217 | p.I132fs*111 | 13.116 |
| PATPFQS | 179..185 | SIDM00541 | p.E144V | 2.4086 |
| PATPFQS | 179..185 | SIDM00118 | p.N92K | 3.7042 |