Q8TEK3
(GRPRLEKLS)
Drug: EPZ5676
Cancer code: COREAD
Cancer type: large_intestine
Drug treatment table
| Degron |
Position |
Sample |
Mutation |
IC50(uM) |
| GRPRLEKLS | 756..764 | SIDM00214 | p.T751P | 366.91 |
| GRPRLEKLS | 756..764 | SIDM01090 | p.E47V | 67.344 |
| GRPRLEKLS | 756..764 | SIDM01090 | p.I48F | 67.344 |
| GRPRLEKLS | 756..764 | SIDM00945 | p.T751P | 396.31 |
| GRPRLEKLS | 756..764 | SIDM00498 | p.P298S | 328.54 |
| GRPRLEKLS | 756..764 | SIDM00217 | p.T1184A | 341.51 |
| GRPRLEKLS | 756..764 | SIDM00217 | p.A1454V | 341.51 |
| GRPRLEKLS | 756..764 | SIDM00216 | p.T1051A | 224.46 |
| GRPRLEKLS | 756..764 | SIDM00216 | p.R1276Q | 224.46 |
| GRPRLEKLS | 756..764 | SIDM00282 | p.F243L | 153.31 |
| GRPRLEKLS | 756..764 | SIDM00282 | p.T984M | 153.31 |
| GRPRLEKLS | 756..764 | SIDM00150 | p.T1317I | 224.8 |
| GRPRLEKLS | 756..764 | SIDM00118 | p.S1457fs*49 | 106.67 |
| GRPRLEKLS | 756..764 | SIDM00660 | p.V1165fs*8 | 452.51 |
| GRPRLEKLS | 756..764 | SIDM00487 | p.T100M | 275.05 |
| GRPRLEKLS | 756..764 | SIDM00837 | p.S1083I | 553.54 |
| GRPRLEKLS | 756..764 | SIDM00193 | p.A483T | 122.08 |
| GRPRLEKLS | 756..764 | SIDM00118 | p.K1203N | 106.67 |
