| Tag |
Content |
| Uniprot ID |
A2A825
|
| Entrez ID |
76166 |
| Genbank protein ID |
|
| Genbank nucleotide ID |
NM_001081174.2 |
| Ensembl protein ID |
ENSMUSP00000095422 |
| Ensembl nucleotide ID |
ENSMUSG00000073733 |
|
Gene name
|
Ciliogenesis and planar polarity effector 2 |
|
Gene symbol
|
Cplane2 |
|
Organism
|
Mus musculus |
|
NCBI taxa ID
|
10090 |
|
Cleft type
|
CLO |
|
Developmental stage
|
|
|
Data sources
|
Manually collected |
| Reference |
25807483 |
|
Functional description
|
Potential effector of the planar cell polarity signaling pathway. Plays a role in targeted membrane trafficking most probably at the level of vesicle fusion with membranes. Involved in cilium biogenesis by regulating the transport of cargo proteins to the basal body and to the apical tips of cilia. More generally involved in exocytosis in secretory cells (By similarity). |
Sequence
| MARPPMHGSV IVPDWHETVE GKEYLACILR KNRRREFGLL ERPVLPPSVV IDTASYKIFV 60
SGKSGVGKTA LVAKLAGLEV PIVHHETTGI QTTVVFWPAK LKASDCVVMF RFEFWDCGES 120
ALKKFDHMLP ACKENADAFL FLFSFTDRAS FEDLPGQLTR VAGEAPGLVK IVIGSKFDQY 180
MHTDVPARDL TAFRQAWELP LFRVKSVPGR RLADGRTLDG RAGLADTAHV LNGLAEQLWH 240
QDQVAAGLLP SSPESAPG 258 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
