Gene: mks1

Basic information

Tag Content
Uniprot ID A3QK09
Entrez ID 556706
Genbank protein ID
Genbank nucleotide ID NM_001077373.2
Ensembl protein ID ENSDARP00000077569
Ensembl nucleotide ID ENSDARG00000059657
Gene name MKS transition zone complex subunit 1
Gene symbol mks1
Organism Danio rerio
NCBI taxa ID 7955
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MADGWCSDNG ESVYRSRDAV KNFRIRVRIQ RVTSTAALSE HLHQQVLSQQ ERGVIELETF 60
STQTASSTDE EELVVAWQEK FFSQYEVDLY QTESNCQTPL ERQYHTDIMA MERSKRRQNQ 120
RIFTYTDFDR FSKWEEQAQS LVIPAQPTPT FLAERMANVR HRRQERRPAE SNVPKSRLIT 180
WEPSEEFVKN SHIINTPVQT MYIMADLGPT GKLGLKENEY VLCTIKADGN GVISIKPDFN 240
NNRGAYRLET EGEKREVWRL YLENASSDIQ AEEKDREQRM YRDLYTRHKD YLNSLVGQDF 300
EMPPPGILRL IVNGEIVSAQ GYEYDNLYVH FFVDLPNNWS SVSSHCLSGV TQTCRTRSIE 360
KEDVAFFSYP FSFETFFHKE DESDGSLPQW PVLYFKVLSL DFWQRFRTEG YGYLVIPSTS 420
GRHRMTCRTW RAVQRGTVAE LRRFFIGGAP ELEDISYVRI PGTFKGERLS RFGFRTQTTG 480
SVTFTLNCIQ HARAFIDAST LKKRRQTVLD QLGGHSQQGS VYNVLEAFQR AHKRMQEARE 540
TLPRDLINTS ALLNSESSA 559

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologMKS1101905689A6QQN3Bos taurusPredictionMore>>
1:1 orthologMKS1102185497A0A452FUL1Capra hircusPredictionMore>>
1:1 orthologMKS154903Q9NXB0Homo sapiensPredictionMore>>
1:1 orthologMks1380718Q5SW45CPO,CLP,CLOMus musculusPublicationMore>>
1:1 orthologMKS1455153H2QDI7Pan troglodytesPredictionMore>>
1:1 orthologMks1F1LSL4Rattus norvegicusPredictionMore>>
1:1 orthologmks1556706A3QK09Danio rerioPredictionMore>>

Gene ontology

GO ID GO Term
GO:0005737 cytoplasm
GO:0036038 MKS complex
GO:0060271 cilium assembly
GO:0060030 dorsal convergence

Functional annotations

Keywords

Keyword ID Keyword Term
KW-0970 Cilium biogenesis/degradation
KW-0963 Cytoplasm
KW-1267 Proteomics identification
KW-1185 Reference proteome

Interpro

InterPro ID InterPro Term
IPR010796 B9_dom

PROSITE

PROSITE ID PROSITE Term
PS51381 B9

Pfam

Pfam ID Pfam Term
PF07162 B9-C2