Gene: Rax

Basic information

Tag Content
Uniprot ID D3ZLM8
Entrez ID
Genbank protein ID
Genbank nucleotide ID
Ensembl protein ID ENSRNOP00000022785
Ensembl nucleotide ID ENSRNOG00000016944
Gene name Retinal homeobox protein Rx
Gene symbol Rax
Organism Rattus norvegicus
NCBI taxa ID 10116
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MHLPGCPPAM ADGSFSLAGH LLRSPGGSTS RLHSIEAILG FTKEDGILDT FPAERSSRGS 60
KERDPRLGAR SACPKAPAGG SESSPPAAPG LVPEFXATRP CYPKEQGEAR PSPGLPVGPA 120
AGDSKLSEEE EPPKKKHRRN RTTFTTYQLH ELERAFEKSH YPDVYSREEL AGKVNLPEVR 180
VQVWFQNRRA KWRRQEKLEV SSMKLQDSPL LSFSRSPPSS ALAPLGGPGS GSGPPGSALP 240
LEPWLGPPLP GGGATALQSL PGFGPPGQGL PASYTPPPPF LNSAPLGPGL QQLGPPPAYP 300
CAPAFGDKFS LEEAYPRNSS IAALRLKAKE HIQAIGKPWQ AL 342

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologRAX108633766A0A452ER72Capra hircusPredictionMore>>
1:1 orthologRAX30062Q9Y2V3Homo sapiensPredictionMore>>
1:1 orthologRax19434O35602CPOMus musculusPublicationMore>>
1:1 orthologRAX468552H2QEL5Pan troglodytesPredictionMore>>
1:1 orthologRaxD3ZLM8Rattus norvegicusPredictionMore>>

Gene ontology

GO ID GO Term
GO:0005634 nucleus
GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0043010 camera-type eye development
GO:0021854 hypothalamus development
GO:0060173 limb development
GO:0007389 pattern specification process

Functional annotations

Keywords

Keyword ID Keyword Term
KW-0217 Developmental protein
KW-0238 DNA-binding
KW-0371 Homeobox
KW-0539 Nucleus
KW-1185 Reference proteome

Interpro

InterPro ID InterPro Term
IPR009057 Homeobox-like_sf
IPR017970 Homeobox_CS
IPR001356 Homeobox_dom
IPR003654 OAR_dom

PROSITE

PROSITE ID PROSITE Term
PS00027 HOMEOBOX_1
PS50071 HOMEOBOX_2
PS50803 OAR

Pfam

Pfam ID Pfam Term
PF00046 Homeodomain
PF03826 OAR