| Tag | Content |
|---|---|
| Uniprot ID | F1Q6W8 |
| Entrez ID | |
| Genbank protein ID | |
| Genbank nucleotide ID | |
| Ensembl protein ID | ENSDARP00000078268 |
| Ensembl nucleotide ID | ENSDARG00000059911 |
| Gene name | Bardet-Biedl syndrome 7 protein homolog |
| Gene symbol | bbs7 |
| Organism | Danio rerio |
| NCBI taxa ID | 7955 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. |
| Sequence | MELNLNHVDY IQVGVTSQKT MKLLPSAGRK STQKVAVADH DGVVSCFGMK KGEAVPVFKS 60 LPGQKISRLE LGGALGTPQE KIFVSSGSEV RGYTKKGKQF LTFEANLTES INAMHVSGAD 120 LFVCASYIYN HYCDCKDQDY YLSGDKINDV LCLPVETVGR IVPILACQDR VLRVLQGSEL 180 QYDVEVPGPP TVLERHDRDG GKGGEEVLYG TADGKLGLVR IAKSGPVTSW ELDNEKKKGG 240 VLCIDTFDIV ADGVKDILVG RDDGTVEVYG LDGSNEPTLR FENVLSESVT SIQGGCVGKE 300 MYDEVLTTTY TGWVSGLTTE PQQMVAGPGE EIKMSQETQG KVAALRAELE QLQLKVLQGR 360 EKYQQSSQSS TAVSAVPVFS INDKFTLCQD DASYSLTLEV QTAIDNLLLQ SDVPIDLLDV 420 DKNSAVVSFS ECDSESNGNF LLATYRCQAN TTRLELKVRS IEGQYGTLQA YVTPRLQPKT 480 CQVRQYQIKP LSLHQRTHTI EQERPMNTLR LTGQFSFAEI HSWVVFCLPE VPEKTPAGEN 540 ITFCFQNTFL GTQLEATYCK GEANFKSDNI STISILKDVL SKEATKRKIN LNISYEVNED 600 SVSHTLRMIH PKLEYQLILA KKVQLIDALK ELQVHEGNAD FLIPEYRSIL DESAQLLEEY 660 KKQPAHLERL YGMITDLFID KFKFKGQNVK TKVSQLLAIL NNYELDSLME FFSEA 715 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | BBS7 | 476092 | E2RQA6 | Canis lupus familiaris | Prediction | More>> | ||
| 1:1 ortholog | BBS7 | 102188122 | A0A452FKE4 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | BBS7 | 100063923 | A0A3Q2H7W6 | Equus caballus | Prediction | More>> | ||
| 1:1 ortholog | BBS7 | 55212 | Q8IWZ6 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Bbs7 | 71492 | Q8K2G4 | CPO,CLP,CLO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | BBS7 | K7BD37 | Pan troglodytes | Prediction | More>> | |||
| 1:1 ortholog | BBS7 | A0A288CFV9 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | Bbs7 | 361930 | Q66H90 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | bbs7 | F1Q6W8 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005930 | axoneme |
| GO:0034464 | BBSome |
| GO:0036064 | ciliary basal body |
| GO:0016020 | membrane |
| GO:0043005 | neuron projection |
| GO:0060271 | cilium assembly |
| GO:0007368 | determination of left/right symmetry |
| GO:0007369 | gastrulation |
| GO:0001947 | heart looping |
| GO:0046907 | intracellular transport |
| GO:0070121 | Kupffer's vesicle development |
| GO:0032402 | melanosome transport |
| GO:1905515 | non-motile cilium assembly |
| GO:0033339 | pectoral fin development |
| GO:0051877 | pigment granule aggregation in cell center |
| GO:0008104 | protein localization |
| GO:0015031 | protein transport |