Gene: Efnb1

Basic information

Tag Content
Uniprot ID Q6P7B6
Entrez ID 25186
Genbank protein ID EDL95949.1; EDL95950.1; AAH61744.1;
Genbank nucleotide ID NM_017089.2
Ensembl protein ID ENSRNOP00000009635
Ensembl nucleotide ID ENSRNOG00000006877
Gene name Ephrin B1, isoform CRA_a
Gene symbol Efnb1
Organism Rattus norvegicus
NCBI taxa ID 10116
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MARPGQRWLS KWLVAMVVLT LCRLATPLAK NLEPVSWSSL NPKFLSGKGL VIYPKIGDKL 60
DIICPRAEAG RPYEYYKLYL VRPEQAAACS TVLDPNVLVT CNKPQQEIRF TIKFQEFSPN 120
YMGLEFKKYH DYYITSTSNG SLEGLENREG GVCRTRTMKI VMKVGQDPNA VTPEQLTTSR 180
PSKESDNTVK TATQAPGRGS QGDSDGKHET VNQQEKSGPG AGGSGSGDTD SFFNSKVALF 240
AAVGAGCVIF LLIIIFLTVL LLKLRKRHRK HTQQRAAALS LSTLASPKGG SGTAGTEPSD 300
IIIPLRTTEN NYCPHYEKVS GDYGHPVYIV QEMPPQSPAN IYYKV 345

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologEFNB1534413A1L570Bos taurusPredictionMore>>
1:1 orthologEFNB1607410E2QSB5Canis lupus familiarisPredictionMore>>
1:1 orthologEFNB1102183496A0A452DVX4Capra hircusPredictionMore>>
1:1 orthologEFNB11947P98172CPO,CL/PHomo sapiensPublicationMore>>
1:1 orthologEfnb113641P52795CPOE14.5Mus musculusPublicationMore>>
1:1 orthologEFNB1473651K7APG7Pan troglodytesPredictionMore>>
1:1 orthologEFNB1A0A287BK49Sus scrofaPredictionMore>>
1:1 orthologEfnb125186Q6P7B6Rattus norvegicusPredictionMore>>
1:1 orthologefnb1114377Q90Z33Danio rerioPredictionMore>>

Gene ontology

GO ID GO Term
GO:0005737 cytoplasm
GO:0016021 integral component of membrane
GO:0045121 membrane raft
GO:0005634 nucleus
GO:0005886 plasma membrane
GO:0046875 ephrin receptor binding
GO:0007411 axon guidance
GO:0009880 embryonic pattern specification
GO:0048013 ephrin receptor signaling pathway
GO:0001755 neural crest cell migration
GO:0042102 positive regulation of T cell proliferation
GO:0031295 T cell costimulation

Functional annotations

Keywords

Keyword ID Keyword Term
KW-1015 Disulfide bond
KW-0472 Membrane
KW-1185 Reference proteome
KW-0732 Signal
KW-0812 Transmembrane
KW-1133 Transmembrane helix

Interpro

InterPro ID InterPro Term
IPR008972 Cupredoxin
IPR031328 Ephrin
IPR034255 Ephrin-B_Ecto
IPR019765 Ephrin_CS
IPR001799 Ephrin_RBD

PROSITE

PROSITE ID PROSITE Term
PS01299 EPHRIN_RBD_1
PS51551 EPHRIN_RBD_2

Pfam

Pfam ID Pfam Term
PF00812 Ephrin