| Tag | Content |
|---|---|
| Uniprot ID | Q8BMQ3; H3BIU0; Q6T3A4; |
| Entrez ID | 242509 |
| Genbank protein ID | BAC26901.1; AAR99388.1; |
| Genbank nucleotide ID | NM_172870.4 |
| Ensembl protein ID | ENSMUSP00000099884; ENSMUSP00000135375; |
| Ensembl nucleotide ID | ENSMUSG00000028487 |
| Gene name | Zinc finger protein basonuclin-2 |
| Gene symbol | Bnc2 |
| Organism | Mus musculus |
| NCBI taxa ID | 10090 |
| Cleft type | CPO |
| Developmental stage | E16.5 |
| Data sources | Manually collected |
| Reference | 19706529 |
| Functional description | Probable transcription factor specific for skin keratinocytes. May play a role in the differentiation of spermatozoa and oocytes. May also play an important role in early urinary-tract development. |
| Sequence | MARFVPSPPP NCLSYKSEGR LGEQDWQAHF KVPCCGVDPS QLESEEAEVD VRERDTQRDR 60 EPKRARDLTL RDSCTDNSMQ FGTRTTAAEP GFMGTWQNAD TNLLFRMSQQ VPLACAGRVL 120 GADFCPNLEE PDQRLEVQAI RCTLVNCTCE CFQPGKINLR TCDQCKHGWV AHALDKLSTQ 180 HLYHPTQVEI VQSNVVFDIS SLMLYGTQAV PVRLKILLDR LFSVLKQEEV LHILHGLGWT 240 LRDYVRGYIL QDAAGKVLDR WAIMSREEEI ITLQQFLRFG ETKSIVELMA IQEKEGQAVA 300 VPSSKTDSDI RTFIESNNRT RSPSLLAHLE NSNPSSIHHF ENIPNSLAFL LPFQYINPVS 360 APLLGLPPNG LLLEQPGLRL REPSISTQNE YNESSESEVS PTPYKSDQTP NRNALTSITN 420 VEPKTEPACV SPIQNSAPVS DLSKTEHPKS SFRIHRMRRM GSASRKGRVF CNACGKTFYD 480 KGTLKIHYNA VHLKIKHRCT IEGCNMVFSS LRSRNRHSAN PNPRLHMPML RNNRDKDLIR 540 ATSGAATPVI ASTKSNLTLT SPGRPPMGFT TPPLDPVLQN PLPSQLVFSG LKTVQPVPPF 600 YRSLLTPGEM VSPPTSLPTS PIIPTSGTIE QHPPPPSEPI VPAVMMGTHE PSADLAPKKK 660 PRKSSMPVKI EKEIIDTADE FDDEDDDPND GGTVVNDMSH DNHCHSQDEM SPGMSVKDFS 720 KHNRTRCISR TEIRRADSMT SEDQEPERDY ENESESSEPK LGEESMEGDE HLHSEVSEKV 780 LMNSERPDEN HSEPSHQDVI KVKEEFTDPT YDMFYMSQYG LYNGGGASMA ALHESFTSSL 840 NYGSPQKFSP EGDLCSSPDP KICYVCKKSF KSSYSVKLHY RNVHLKEMHV CTVAGCNAAF 900 PSRRSRDRHS ANINLHRKLL TKELDDMSLD SSQPSLSKDL RDEFLMKIYG AQHPLGLDGR 960 EDASSPAGTE DSHLNGYGRG MAEDYMVLDL STTSSLQSSS SVHSSRESDA GSDEGILLDD 1020 IDGASDSGES THKAEAPTLP GSLGAEVSGS LMFSSLSGSN GGIMCNICHK MYSNKGTLRV 1080 HYKTVHLREM HKCKVPGCNM MFSSVRSRNR HSQNPNLHKN IPFTSID 1127 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | BNC2 | F1PDU8 | Canis lupus familiaris | Prediction | More>> | |||
| 1:1 ortholog | BNC2 | 102186591 | A0A452G5Q4 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | BNC2 | 54796 | Q6ZN30 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Bnc2 | 242509 | Q8BMQ3 | CPO | E16.5 | Mus musculus | Publication | More>> |
| 1:1 ortholog | BNC2 | A0A2I3TJH0 | Pan troglodytes | Prediction | More>> | |||
| 1:1 ortholog | A0A480LWE7 | Sus scrofa | Prediction | More>> | ||||
| 1:1 ortholog | Bnc2 | 298189 | D3ZZ22 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | bnc2 | 559327 | C7DZJ6 | Danio rerio | Prediction | More>> |
| GO ID | GO Term | Evidence |
|---|---|---|
| GO:0003677 | DNA binding | IDA |
| GO:0046872 | metal ion binding | IEA |
| GO ID | GO Term | Evidence |
|---|---|---|
| GO:0003416 | endochondral bone growth | IMP |
| GO:0043586 | tongue development | IMP |
| GO:0060021 | roof of mouth development | IMP |
| GO:0060485 | mesenchyme development | IMP |
| GO ID | GO Term | Evidence |
|---|---|---|
| GO:0005634 | nucleus | IDA |
| GO:0005654 | nucleoplasm | ISO |
| Reactome ID | Reactome Term | Evidence |
|---|
| Pfam ID | Pfam Term |
|---|---|
| PF00096 | zf-C2H2 |