Gene: Prss35

Basic information

Tag Content
Uniprot ID Q8C0F9; Q8C0D6; Q8C0L5;
Entrez ID 244954
Genbank protein ID ABB46197.1; BAC27073.1; BAC27491.1; AAH75675.1; BAC27392.1;
Genbank nucleotide ID NM_178738.3; XM_006511172.3; XM_006511171.3; XM_006511170.3;
Ensembl protein ID ENSMUSP00000137445; ENSMUSP00000035271;
Ensembl nucleotide ID ENSMUSG00000033491
Gene name Inactive serine protease 35
Gene symbol Prss35
Organism Mus musculus
NCBI taxa ID 10090
Cleft type
Developmental stage E12.0, E13.0, E14.0, E14.5
Data sources Homology search
Reference
Functional description
Sequence
MENTLLWLVI LIPGWALSDG SETELDFTWH LSRIPQVVSE NTIHLASPTF QADAGVVKAT 60
VCGIECQEEL PAPSLSQLEE SLSYETIFEN GTRTLTRVKV QGLVLEPTRN SSVKGAHPRR 120
RRQVYGTDSR FSILDKRFAT NFPFNTAVKL STGCSGTLVS PNHVLTAAHC VHDGKDYVKG 180
SKKLRVGVLK MRNKGGRKKR RGSKRSRREA ESAGQSQAHL RESTTQRPGK KSRRGPRVTQ 240
GRPSFQWTRV KSTHIPKGWV RGENGGLALD YDYALLELKR AHKQQHMELG VSPTITKLPG 300
GRIHFSGFDN DRDEQLVYRF CSVSEESNDL LYQYCDAEAG STGSGIYLRL KEPGQKNWKR 360
KIVAVYSGHQ WVDVHGVQKD YNVAVRITPL KYAQICLWIH GNAANCAYG 409

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Gene expression information

Gene expression during embryonic days (E11.5~E18.5) ~ adult days (Ps) in the lip and palate tissues. (X-axis: days, Y-axis: tissues)

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Protein structural annotations

3D structure in PDB database

There is no related protein structure for this gene.

Protein disorder information

Orthologous information

Identified variants/mutations related to cleft phenotype

Other genetic variants/mutations

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Gene Ontology (GO)/biological pathways

GO:Molecular Function


GO:Biological Process


GO:Cellular Component


Reactome Pathway

Functional annotations

Keywords

Interpro

PROSITE

Pfam

Protein-miRNA interaction