Gene: Ovca2

Basic information

Tag Content
Uniprot ID Q9D7E3
Entrez ID 246257
Genbank protein ID BAC26910.1; AAM14630.1; BAC28331.1; BAB26208.1;
Genbank nucleotide ID NM_027136.3
Ensembl protein ID ENSMUSP00000071493
Ensembl nucleotide ID ENSMUSG00000038268
Gene name Esterase OVCA2
Gene symbol Ovca2
Organism Mus musculus
NCBI taxa ID 10090
Cleft type CPO
Developmental stage
Data sources Manually collected
Reference 14744934
Functional description
Sequence
MAARQTLRVL CLAGFRQSER GFREKTGALR KTLRGRAELV CLSGPHPVPE AAAPEGSCPD 60
SGPCSPEEQP RGWWFSEEEA DVFSALEEST VCRGLQEALE TVARALDTLG PFDGLLGFSQ 120
GAALAAYVCA LGQAGDPRFP LPRFIILVSG FCPRGLKEPI LQSPMSLPSL HVFGDTDRVI 180
PSQESMQLAS RFLGAVTLTH SGGHFIPAAA SQRQAYLKFL DQFAE 225

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein structural annotations

3D structure in PDB database

There is no related protein structure for this gene.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologOVCA2513845Q3SZ07Bos taurusPredictionMore>>
1:1 orthologOVCA2E2QZ82Canis lupus familiarisPredictionMore>>
1:1 orthologOVCA2A0A452G6K8Capra hircusPredictionMore>>
1:1 orthologOVCA2F6QJ19Equus caballusPredictionMore>>
1:1 orthologOVCA2124641Q8WZ82Homo sapiensPredictionMore>>
1:1 orthologOvca2246257Q9D7E3CPOMus musculusPublicationMore>>
1:1 orthologA0A4X1U7E4Sus scrofaPredictionMore>>
1:1 orthologovca2553576Q503Y4Danio rerioPredictionMore>>

Other genetic variants/mutations

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Gene Ontology (GO)/biological pathways

GO:Molecular Function

GO ID GO Term Evidence
GO:0003674 molecular_functionND
GO:0016787 hydrolase activityIEA

GO:Biological Process

GO ID GO Term Evidence
GO:0032526 response to retinoic acidISO
GO:0032526 response to retinoic acidIBA

GO:Cellular Component

GO ID GO Term Evidence
GO:0005634 nucleusIDA
GO:0005634 nucleusIBA
GO:0005737 cytoplasmISO
GO:0005737 cytoplasmIDA
GO:0005737 cytoplasmIBA

Reactome Pathway

Reactome ID Reactome Term Evidence

Functional annotations

Keywords

Keyword ID Keyword Term
KW-0378 Hydrolase
KW-1185 Reference proteome

Interpro

InterPro ID InterPro Term
IPR029058 AB_hydrolase
IPR005645 FSH_dom

PROSITE

PROSITE ID PROSITE Term

Pfam

Pfam ID Pfam Term
PF03959 FSH1