Gene: Golga5

Basic information

Tag Content
Uniprot ID Q9QYE6; O88317; Q3TGE7; Q3U6S5; Q3UUF9;
Entrez ID 27277
Genbank protein ID AAH16883.1; BAA33010.1; BAE40601.1; AAF21628.1; BAE31649.1; AAH86782.1; BAE31289.1; BAE23668.1;
Genbank nucleotide ID NM_001199004.1; NM_013747.4; XM_006515935.3;
Ensembl protein ID ENSMUSP00000137305; ENSMUSP00000021609;
Ensembl nucleotide ID ENSMUSG00000021192
Gene name Golgin subfamily A member 5
Gene symbol Golga5
Organism Mus musculus
NCBI taxa ID 10090
Cleft type CPO
Developmental stage
Data sources Manually collected
Reference 28509431
Functional description Involved in maintaining Golgi structure. Stimulates the formation of Golgi stacks and ribbons. Involved in intra-Golgi retrograde transport (By similarity).
Sequence
MSWFADLAGR AEDLLNRVDQ GAATALRKEN TSNIFYSKNT DYPELQQQNT DSNYQTGQKA 60
NYISSAADNI RHQKATILAG TANVKVGSRT VGDATHPTEH ASAPRPSSQF VRRKKSEPDD 120
ELLFDFLNSS QKEPTGRVEV KKEKGRAPVS PSSPSGVSSV NTSVTTTKAM GGNAGSQSPG 180
VNSSDSVPEV HKEPSEESTA PSATSEEHSS TPSDGSSRSQ ELSNLRLENQ LLRNEVQSLN 240
QEMASLLQRS KETQEELNKA RVRVEKWNVD NSKSDRITRE LRAQVDDLTE AVAAKDSQLA 300
VLKVRLQEAD QVLSSRTEAL EALRSEKSRI MQDHKEGSSL QNQALQTLQE RLHEADATLK 360
REQESYKQMQ SEFAARLNKM EVDRQNLAEA VTLAERKYSE EKKKVDELQQ QVKLHRASLE 420
SAKQELVDYK QKATRILQSK EKLINSLKEG SSFEGLESST ASSMELEELR HEKEMQKEEI 480
QKLMGQMHQL RSELQDMEAQ QVSEAESARE QLQDLQDQIA KQRTSKQELE TELERMKQEF 540
RYMEEDLHRT KNTLQSRIKD REEEIQKLRN QLTNKTLSNS SQSELESRLH QLTETLIQKQ 600
TMLESLSTEK NSLVFQLERL EQQVHSASSG PNSGSAINMS GVDSGEGTRL RNVPVLFNDT 660
ETNLAGMYGK VRKAASSIDQ FSIRLGIFLR RYPIARVFVI IYMALLHLWV MIVLLTYSPE 720
MHHDQPYGK 729

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein structural annotations

3D structure in PDB database

There is no related protein structure for this gene.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologGOLGA5510412A5D7A5Bos taurusPredictionMore>>
1:1 orthologGOLGA5480233E2QWJ2Canis lupus familiarisPredictionMore>>
1:1 orthologGOLGA5102168492A0A452E4E7Capra hircusPredictionMore>>
1:1 orthologGOLGA5100053313A0A3Q2KJX3Equus caballusPredictionMore>>
1:1 orthologGOLGA59950Q8TBA6Homo sapiensPredictionMore>>
1:1 orthologGolga527277Q9QYE6CPOMus musculusPublicationMore>>
1:1 orthologGOLGA5H2Q8T6Pan troglodytesPredictionMore>>
1:1 orthologGOLGA5100346310G1TA69Oryctolagus cuniculusPredictionMore>>
1:1 orthologGolga5299258G3V6Z7Rattus norvegicusPredictionMore>>
1:1 orthologgolga5B8A4N9Danio rerioPredictionMore>>

Other genetic variants/mutations

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Gene Ontology (GO)/biological pathways

GO:Molecular Function

GO ID GO Term Evidence
GO:0005515 protein bindingIPI
GO:0017137 Rab GTPase bindingISO
GO:0030674 protein binding, bridgingISO
GO:0042803 protein homodimerization activityISS
GO:0042803 protein homodimerization activityISO

GO:Biological Process

GO ID GO Term Evidence
GO:0000301 retrograde transport, vesicle recycling within GolgiISO
GO:0000301 retrograde transport, vesicle recycling within GolgiIBA
GO:0007030 Golgi organizationISS
GO:0007030 Golgi organizationISO
GO:0007030 Golgi organizationIBA
GO:0048193 Golgi vesicle transportISS
GO:0048193 Golgi vesicle transportISO

GO:Cellular Component

GO ID GO Term Evidence
GO:0000137 Golgi cis cisternaISO
GO:0000138 Golgi trans cisternaISO
GO:0000139 Golgi membraneISO
GO:0000139 Golgi membraneIBA
GO:0000139 Golgi membraneIDA
GO:0005794 Golgi apparatusISS
GO:0005794 Golgi apparatusISO
GO:0005797 Golgi medial cisternaISO
GO:0005801 cis-Golgi networkISO
GO:0016021 integral component of membraneISO
GO:0030663 COPI-coated vesicle membraneISO
GO:0031985 Golgi cisternaISO
GO:0031985 Golgi cisternaIBA

Reactome Pathway

Reactome ID Reactome Term Evidence

Functional annotations

Keywords

Keyword ID Keyword Term
KW-0007 Acetylation
KW-0175 Coiled coil
KW-0333 Golgi apparatus
KW-0472 Membrane
KW-0488 Methylation
KW-0597 Phosphoprotein
KW-1185 Reference proteome
KW-0812 Transmembrane
KW-1133 Transmembrane helix

Interpro

InterPro ID InterPro Term
IPR019177 Golgin_subfamily_A_member_5

PROSITE

PROSITE ID PROSITE Term

Pfam

Pfam ID Pfam Term
PF09787 Golgin_A5