ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

RAMP3

Full Name:

receptor (G protein-coupled) activity modifying protein 3

Organism:

Homo sapiens (Human)

Chromosome:

Genetic Location:

7p13-p12

Physical Location:

45163891-45190373 on NC_000007.12

Gene Type:

protein-coding

Orthologs:

This gene has Rat: 56820 ortholog(s) in other dataset(s).

Gene in Ethanol Study Datasets

Gene Information

Original ID1:		AJ001016
Fold Change:		2.03

Dataset Information

Name:		15236863
Method:		Microarray
Tissue:		Prefrontal cortex
Phenotype:		Alcohol dependence (AD)/Alcohol abuse/Alcoholism
Publication:		Iwamoto et al. Neurosci Res. (2004) Decreased expression of NEFH and PCP4/PEP19 in the prefrontal cortex of alcoholics. PubMed
Summary:		We have performed oligonucleotide microarray analysis in postmortem prefrontal cortices of alcoholics. Among about 12,000 genes represented on microarray, a total of 79 genes showed differential expression changes in alcoholics compared with control subjects, consisting of 54 up- and 25 down-regulated genes.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_005856.2	NP_005847.1	NC_000007.12 range: 45163891..45190373

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005764	lysosome	Cellular Component	TAS (10882736)
GO:0005886	plasma membrane	Cellular Component	TAS (9620797)
GO:0005887	integral to plasma membrane	Cellular Component	TAS (9620797)
GO:0004872	receptor activity	Molecular Function	IEA
GO:0008565	protein transporter activity	Molecular Function	IEA
GO:0006886	intracellular protein transport	Biological Process	IEA
GO:0006898	receptor-mediated endocytosis	Biological Process	TAS (10882736)
GO:0007166	cell surface receptor linked signal transduction	Biological Process	NR
GO:0008277	regulation of G-protein coupled receptor protein signaling pathway	Biological Process	IEA