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Gene Information
Gene ID:3304
Symbol:HSPA1B
Full Name:heat shock 70kDa protein 1B
Alias:HSP70-1B|HSP70-2|HSPA1A
Organism:Homo sapiens (Human)
Chromosome:6
Genetic Location:6p21.3
Physical Location:31903502-31906009 on NC_000006.10
Gene Type:protein-coding
Orthologs:This gene has Mouse: 15511 ortholog(s) in other dataset(s).
Gene in Ethanol Study Datasets
Gene Information
Original ID1:M59830
Fold Change:6.17
Dataset Information
Name:15236863
Method:Microarray
Tissue:Prefrontal cortex
Phenotype:Alcohol dependence (AD)/Alcohol abuse/Alcoholism
Publication:Iwamoto et al. Neurosci Res. (2004) Decreased expression of NEFH and PCP4/PEP19 in the prefrontal cortex of alcoholics. PubMed
Summary:We have performed oligonucleotide microarray analysis in postmortem prefrontal cortices of alcoholics. Among about 12,000 genes represented on microarray, a total of 79 genes showed differential expression changes in alcoholics compared with control subjects, consisting of 54 up- and 25 down-regulated genes.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_005346.4NP_005337.2NC_000006.10 range: 31903502..31906009
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0005783endoplasmic reticulumCellular ComponentTAS (16130169)
GO:0005634nucleusCellular ComponentTAS (10205060)
GO:0005737cytoplasmCellular ComponentTAS (16130169)
GO:0005739mitochondrionCellular ComponentTAS (16130169)
GO:0000166nucleotide bindingMolecular FunctionIEA
GO:0005524ATP bindingMolecular FunctionIEA
GO:0051082unfolded protein bindingMolecular FunctionTAS (16130169)
GO:0006402mRNA catabolic processBiological ProcessTAS (10205060)
GO:0006916anti-apoptosisBiological ProcessTAS (16130169)
GO:0006986response to unfolded proteinBiological ProcessTAS (10859165)
Other Database Cross Links
NCBI Entrez Gene:3304
HGNC:5233
Ensembl:ENSG00000204388
MIM:603012
HPRD:06784
HuGE Navigator:3304
dbSNP:HSPA1B
GeneCard:HSPA1B
AceView:HSPA1B