ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

NFIA

Full Name:

nuclear factor I/A

Alias:

DKFZp434L0422|KIAA1439|NFI-L

Organism:

Homo sapiens (Human)

Chromosome:

Genetic Location:

1p31.3-p31.2

Physical Location:

61320880-61694623 on NC_000001.9

Gene Type:

protein-coding

Orthologs:

This gene has Mouse: 18027 Rat: 25492 ortholog(s) in other dataset(s).

Gene in Ethanol Study Datasets

Gene Information

Original ID1:		NFIA
Original ID2:		H08637

Dataset Information

Name:		11093800
Method:		Microarray
Tissue:		SH-SY5Y neuroblastoma cells
Phenotype:		Ethanol response
Publication:		Thibault et al. Mol Pharmacol. (2000) Expression profiling of neural cells reveals specific patterns of ethanol-responsive gene expression. PubMed
Summary:		We used oligonucleotide arrays to study nearly 6000 genes in human SH-SY5Y neuroblastoma cells exposed to chronic ethanol. A set of 42 genes had consistently increased or decreased mRNA abundance after 3 days of ethanol treatment.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_005595.1	NP_005586.1	NC_000001.9 range: 61320880..61694623

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005622	intracellular	Cellular Component	IEA
GO:0005634	nucleus	Cellular Component	IDA (15684392)
GO:0005634	nucleus	Cellular Component	IEA
GO:0005634	nucleus	Cellular Component	NAS (7590749)
GO:0003700	transcription factor activity	Molecular Function	IEA
GO:0003700	transcription factor activity	Molecular Function	NAS (7590749)
GO:0008134	transcription factor binding	Molecular Function	IPI (15684392)
GO:0006355	regulation of transcription, DNA-dependent	Biological Process	NAS (7590749)
GO:0006355	regulation of transcription, DNA-dependent	Biological Process	IEA
GO:0006350	transcription	Biological Process	IEA
GO:0006260	DNA replication	Biological Process	IEA
GO:0019079	viral genome replication	Biological Process	NAS (7590749)