ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Full Name:

pyruvate carboxylase

Alias:

PCB

Organism:

Homo sapiens (Human)

Chromosome:

Genetic Location:

11q13.4-q13.5

Physical Location:

66372572-66482422 on NC_000011.8, complement

Gene Type:

protein-coding

Orthologs:

This gene has Mouse: 18563 Fly: 36020 ortholog(s) in other dataset(s).

Gene in Ethanol Study Datasets

Gene Information

Original ID1:

Dataset Information

Name:		Literature Search
Method:		Literature search
Summary:		We search all human protein coding gene names and the keywords Alcohol or Ethanol or Alcoholism in the title or abstract of all PUBMED publications. For those gene name less than 3 characters or search result hits more than 100, we use the full name to search again and manually check the results to reduce false positive.

Gene Refseq Sequence Annotation

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005759	mitochondrial matrix	Cellular Component	IEA
GO:0005737	cytoplasm	Cellular Component	IEA
GO:0005739	mitochondrion	Cellular Component	IDA (16729965)
GO:0005759	mitochondrial matrix	Cellular Component	EXP (12437512)
GO:0016874	ligase activity	Molecular Function	IEA
GO:0009374	biotin binding	Molecular Function	TAS (8048912)
GO:0000166	nucleotide binding	Molecular Function	IEA
GO:0005524	ATP binding	Molecular Function	TAS (8048912)
GO:0004736	pyruvate carboxylase activity	Molecular Function	TAS (7918683)
GO:0004736	pyruvate carboxylase activity	Molecular Function	EXP (12437512)
GO:0030145	manganese ion binding	Molecular Function	IEA
GO:0006094	gluconeogenesis	Biological Process	IEA
GO:0008152	metabolic process	Biological Process	IEA
GO:0008610	lipid biosynthetic process	Biological Process	IEA