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Gene Information
Gene ID:53379
Full Name:heterogeneous nuclear ribonucleoprotein A2/B1
Organism:Mus musculus (Mouse)
Physical Location:51410432-51419892 on NC_000072.5, complement
Gene Type:protein-coding
Human Ortholog:GeneID: 3181    Symbol (Name): HNRNPA2B1 (heterogeneous nuclear ribonucleoprotein A2/B1)
Ortholog Status:The human GeneID 3181 is also in human dataset(s).
Gene in Ethanol Study Datasets
Gene Information
Original ID1:Hnrpa2b1
Original ID2:AF073993
Dataset Information
Tissue:Nucleus accumbens, prefrontal cortex, and ventral tegmental area
Phenotype:Acute ethanol response
Publication:Kerns et al. J Neurosci. (2005) Ethanol-responsive brain region expression networks: implications for behavioral responses to acute ethanol in DBA/2J versus C57BL/6J mice. PubMed
Summary:The inbred mouse strains DBA/2J and C57BL/6J exhibit contrasting acute behavioral responses to ethanol. We used oligonucleotide microarrays and bioinformatics methods to characterize patterns of gene expression in three brain regions of the mesolimbic reward pathway of these strains. Expression profiling included examination of both differences in gene expression 4 h after acute ethanol (2 g/kg). Using a rigorous stepwise method for microarray analysis, we identified 307 ethanol-regulated genes in the nucleus accumbens, prefrontal cortex, and ventral tegmental area.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_016806.2NP_058086.2NC_000072.5 range: 51410432..51419892, complement
NM_182650.3NP_872591.1NC_000072.5 range: 51410432..51419892, complement
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0005634nucleusCellular ComponentIEA
GO:0005681spliceosomeCellular ComponentIEA
GO:0030529ribonucleoprotein complexCellular ComponentIEA
GO:0000166nucleotide bindingMolecular FunctionIEA
GO:0003676nucleic acid bindingMolecular FunctionIEA
GO:0003723RNA bindingMolecular FunctionIEA
GO:0005515protein bindingMolecular FunctionIPI (16294306)
GO:0006397mRNA processingBiological ProcessIEA
GO:0008380RNA splicingBiological ProcessIEA
Other Database Cross Links
NCBI Entrez Gene:53379