ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

5925

Symbol:

RB1

Full Name:

retinoblastoma 1 (including osteosarcoma)

Alias:

OSRC|RB|p105-Rb|pRb|pp110

Organism:

Homo sapiens (Human)

Chromosome:

Genetic Location:

13q14.2

Physical Location:

47775883-47954026 on NC_000013.9

Gene Type:

protein-coding

Orthologs:

This gene has Mouse: 19645 Rat: 24708 ortholog(s) in other dataset(s).

Gene in Ethanol Study Datasets

Gene Information

Original ID1:

RB1

Dataset Information

Name:		Literature Search
Method:		Literature search
Summary:		We search all human protein coding gene names and the keywords Alcohol or Ethanol or Alcoholism in the title or abstract of all PUBMED publications. For those gene name less than 3 characters or search result hits more than 100, we use the full name to search again and manually check the results to reduce false positive.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_000321.2	NP_000312.2	NC_000013.9 range: 47775883..47954026

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005634	nucleus	Cellular Component	NAS (3413073)
GO:0016605	PML body	Cellular Component	IDA (9448006)
GO:0005654	nucleoplasm	Cellular Component	EXP (9190208\|11931757\|14527418)
GO:0000785	chromatin	Cellular Component	TAS (3657987)
GO:0005634	nucleus	Cellular Component	TAS (3657987)
GO:0019900	kinase binding	Molecular Function	IDA (16286473)
GO:0005515	protein binding	Molecular Function	IPI (7542657\|9395244\|9448006\|9858607\|11073990\|16286473)
GO:0003713	transcription coactivator activity	Molecular Function	NAS (15572661)
GO:0003700	transcription factor activity	Molecular Function	TAS (3657987)
GO:0003674	molecular_function	Molecular Function	ND (3413073)
GO:0050681	androgen receptor binding	Molecular Function	NAS (15572661)
GO:0030308	negative regulation of cell growth	Biological Process	TAS (7542657)
GO:0030521	androgen receptor signaling pathway	Biological Process	NAS (15572661)
GO:0043550	regulation of lipid kinase activity	Biological Process	IDA (16286473)
GO:0045786	negative regulation of cell cycle	Biological Process	IEA
GO:0045893	positive regulation of transcription, DNA-dependent	Biological Process	NAS (15572661)
GO:0000075	cell cycle checkpoint	Biological Process	TAS (10825186)
GO:0016568	chromatin modification	Biological Process	IEA
GO:0006469	negative regulation of protein kinase activity	Biological Process	IPI (9858607)
GO:0006355	regulation of transcription, DNA-dependent	Biological Process	NAS (3413073)
GO:0006350	transcription	Biological Process	IEA
GO:0000279	M phase	Biological Process	NAS (7542657)
GO:0000122	negative regulation of transcription from RNA polymerase II promoter	Biological Process	TAS (9491888)
GO:0051318	G1 phase	Biological Process	TAS (7542657)