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Gene Information
Gene ID:5925
Full Name:retinoblastoma 1 (including osteosarcoma)
Organism:Homo sapiens (Human)
Genetic Location:13q14.2
Physical Location:47775883-47954026 on NC_000013.9
Gene Type:protein-coding
Orthologs:This gene has Mouse: 19645 Rat: 24708 ortholog(s) in other dataset(s).
Gene in Ethanol Study Datasets
Gene Information
Original ID1:RB1
Dataset Information
Name:Literature Search
Method:Literature search
Summary:We search all human protein coding gene names and the keywords Alcohol or Ethanol or Alcoholism in the title or abstract of all PUBMED publications. For those gene name less than 3 characters or search result hits more than 100, we use the full name to search again and manually check the results to reduce false positive.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_000321.2NP_000312.2NC_000013.9 range: 47775883..47954026
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0005634nucleusCellular ComponentNAS (3413073)
GO:0016605PML bodyCellular ComponentIDA (9448006)
GO:0005654nucleoplasmCellular ComponentEXP (9190208|11931757|14527418)
GO:0000785chromatinCellular ComponentTAS (3657987)
GO:0005634nucleusCellular ComponentTAS (3657987)
GO:0019900kinase bindingMolecular FunctionIDA (16286473)
GO:0005515protein bindingMolecular FunctionIPI (7542657|9395244|9448006|9858607|11073990|16286473)
GO:0003713transcription coactivator activityMolecular FunctionNAS (15572661)
GO:0003700transcription factor activityMolecular FunctionTAS (3657987)
GO:0003674molecular_functionMolecular FunctionND (3413073)
GO:0050681androgen receptor bindingMolecular FunctionNAS (15572661)
GO:0030308negative regulation of cell growthBiological ProcessTAS (7542657)
GO:0030521androgen receptor signaling pathwayBiological ProcessNAS (15572661)
GO:0043550regulation of lipid kinase activityBiological ProcessIDA (16286473)
GO:0045786negative regulation of cell cycleBiological ProcessIEA
GO:0045893positive regulation of transcription, DNA-dependentBiological ProcessNAS (15572661)
GO:0000075cell cycle checkpointBiological ProcessTAS (10825186)
GO:0016568chromatin modificationBiological ProcessIEA
GO:0006469negative regulation of protein kinase activityBiological ProcessIPI (9858607)
GO:0006355regulation of transcription, DNA-dependentBiological ProcessNAS (3413073)
GO:0006350transcriptionBiological ProcessIEA
GO:0000279M phaseBiological ProcessNAS (7542657)
GO:0000122negative regulation of transcription from RNA polymerase II promoterBiological ProcessTAS (9491888)
GO:0051318G1 phaseBiological ProcessTAS (7542657)
Other Database Cross Links
NCBI Entrez Gene:5925
HuGE Navigator:5925