ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

RPL28

Full Name:

ribosomal protein L28

Alias:

FLJ43307

Organism:

Homo sapiens (Human)

Chromosome:

Genetic Location:

19q13.4

Physical Location:

60589111-60595264 on NC_000019.8

Gene Type:

protein-coding

Orthologs:

This gene has Rat: 64638 ortholog(s) in other dataset(s).

Gene in Ethanol Study Datasets

Gene Information

Original ID1:		RPL28
Original ID2:		R60751

Dataset Information

Name:		11093800
Method:		Microarray
Tissue:		SH-SY5Y neuroblastoma cells
Phenotype:		Ethanol response
Publication:		Thibault et al. Mol Pharmacol. (2000) Expression profiling of neural cells reveals specific patterns of ethanol-responsive gene expression. PubMed
Summary:		We used oligonucleotide arrays to study nearly 6000 genes in human SH-SY5Y neuroblastoma cells exposed to chronic ethanol. A set of 42 genes had consistently increased or decreased mRNA abundance after 3 days of ethanol treatment.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_000991.3	NP_000982.2	NC_000019.8 range: 60589111..60595264

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0022625	cytosolic large ribosomal subunit	Cellular Component	TAS (7772601)
GO:0005840	ribosome	Cellular Component	IEA
GO:0005829	cytosol	Cellular Component	EXP (14567916)
GO:0005622	intracellular	Cellular Component	IEA
GO:0005515	protein binding	Molecular Function	IPI (17353931)
GO:0003735	structural constituent of ribosome	Molecular Function	TAS (7772601)
GO:0003735	structural constituent of ribosome	Molecular Function	IEA
GO:0003723	RNA binding	Molecular Function	TAS (7772601)
GO:0006412	translation	Biological Process	IEA
GO:0006414	translational elongation	Biological Process	EXP (15189156)