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Gene Information
Gene ID:64638
Symbol:Rpl28
Full Name:ribosomal protein L28
Organism:Rattus norvegicus (Rat)
Chromosome:1
Genetic Location:1q12
Physical Location:67768596-67771157 on NC_005100.2, complement
Gene Type:protein-coding
Human Ortholog:GeneID: 6158    Symbol (Name): RPL28 (ribosomal protein L28)
Ortholog Status:The human GeneID 6158 is also in human dataset(s).
Gene in Ethanol Study Datasets
Gene Information
Original ID1:Rpl28
Fold Change:1.14
P Value:0.002
Note:Differential expression between ethanol and saccharin groups in nucleus accumbens
Dataset Information
Name:18405950
Method:Microarray
Tissue:Nucleus accumbens and amygdala
Phenotype:Ethanol self-administration, alcohol-preferring
Publication:Rodd et al. Pharmacol Biochem Behav. (2008) Differential gene expression in the nucleus accumbens with ethanol self-administration in inbred alcohol-preferring rats. PubMed
Summary:The current study examined the effects of operant ethanol (EtOH) self-administration on gene expression kin the nucleus accumbens (ACB) and amygdala (AMYG) of inbred alcohol-preferring (iP) rats. Rats self-trained on a standard two-lever operant paradigm to administer either water-water, EtOH (15% v/v)-water, or saccharin (SAC; 0.0125% g/v)-water. For the ACB, there were 513 significant differences at the p < 0.01 level in named genes: 55 between SAC and water; 215 between EtOH and water, and 243 between EtOH and SAC. In the case of the AMYG (p < 0.01), there were 48 between SAC and water, 23 between EtOH and water, and 63 between EtOH and SAC group.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_022697.2NP_073188.2NC_005100.2 range: 67768596..67771157, complement
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0005622intracellularCellular ComponentIEA
GO:0005840ribosomeCellular ComponentIEA
GO:0003735structural constituent of ribosomeMolecular FunctionIEA
GO:0005515protein bindingMolecular FunctionISS
GO:0006412translationBiological ProcessIEA
Other Database Cross Links
NCBI Entrez Gene:64638
RGD:621193
Ensembl:ENSRNOG00000017127
dbSNP:Rpl28