| Gene Information |
| Gene ID: | | 84050 |
| Symbol: | | Enpp2 |
| Full Name: | | ectonucleotide pyrophosphatase/phosphodiesterase 2 |
| Alias: | | MGC93258 |
| Organism: | | Rattus norvegicus (Rat) |
| Chromosome: | | 7 |
| Genetic Location: | | 7q31 |
| Physical Location: | | 91295823-91377849 on NC_005106.2, complement |
| Gene Type: | | protein-coding |
| Human Ortholog: | | GeneID: 5168 Symbol (Name): ENPP2 (ectonucleotide pyrophosphatase/phosphodiesterase 2 (autotaxin)) |
| Ortholog Status: | | The human GeneID 5168 is also in human dataset(s). |
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| Gene in Ethanol Study Datasets |
| Gene Information | | Original ID1: | | D28560 | | Fold Change: | | 2.7 | | Tissue: | | Amygdala |
| | Dataset Information | | Name: | | 11772933 | | Method: | | Microarray | | Tissue: | | Frontal cortex and amygdala | | Phenotype: | | Ethanol response | | Publication: | | Rimondini et al FASEB J. (2002) Long-lasting increase in voluntary ethanol consumption and transcriptional regulation in the rat brain after intermittent exposure to alcohol. PubMed | | Summary: | | Here we demonstrate that rats subjected to repeated cycles of intoxication and withdrawal develop a marked and long-lasting increase in voluntary ethanol intake. Exposure-induced but not spontaneous alcohol intake is antagonized by acamprosate, a compound clinically effective in human alcoholism. Expression analysis of cingulate cortex and amygdala reveals a set of long-term up-regulated transcripts in this model. Here lists the gene expression changes 3 wk after termination of 7 wk of intermittent ethanol exposure. Fold change values are ethanol exposed vs. control rats. |
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| Gene Refseq Sequence Annotation |
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| Other Database Cross Links |
| NCBI Entrez Gene: | | 84050 |
| RGD: | | 69298 |
| Ensembl: | | ENSRNOG00000004089 |
| dbSNP: | | Enpp2 |
