ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

PKP4

Full Name:

plakophilin 4

Alias:

FLJ31261|FLJ42243|p0071

Organism:

Homo sapiens (Human)

Chromosome:

Genetic Location:

2q23-q31

Physical Location:

159021721-159246186 on NC_000002.10

Gene Type:

protein-coding

Orthologs:

This gene has Mouse: 227937 ortholog(s) in other dataset(s).

Gene in Ethanol Study Datasets

Gene Information

Original ID1:		X81889
Fold Change:		2.45

Dataset Information

Name:		15236863
Method:		Microarray
Tissue:		Prefrontal cortex
Phenotype:		Alcohol dependence (AD)/Alcohol abuse/Alcoholism
Publication:		Iwamoto et al. Neurosci Res. (2004) Decreased expression of NEFH and PCP4/PEP19 in the prefrontal cortex of alcoholics. PubMed
Summary:		We have performed oligonucleotide microarray analysis in postmortem prefrontal cortices of alcoholics. Among about 12,000 genes represented on microarray, a total of 79 genes showed differential expression changes in alcoholics compared with control subjects, consisting of 54 up- and 25 down-regulated genes.

Gene Refseq Sequence Annotation

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005737	cytoplasm	Cellular Component	IEA
GO:0005856	cytoskeleton	Cellular Component	IEA
GO:0005911	intercellular junction	Cellular Component	TAS (8937994)
GO:0005198	structural molecule activity	Molecular Function	IEA
GO:0005488	binding	Molecular Function	IEA
GO:0005515	protein binding	Molecular Function	IEA
GO:0007155	cell adhesion	Biological Process	NAS (8937994)