| General information | Literature | Expression | Regulation | Variant | Interaction |
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Basic Information |
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|---|---|
Gene ID | 10059 |
Name | DNM1L |
Synonym | DLP1|DRP1|DVLP|DYMPLE|DYNIV-11|EMPF|HDYNIV|VPS1;dynamin 1-like;DNM1L;dynamin 1-like |
Definition | Dnm1p/Vps1p-like protein|dynamin family member proline-rich carboxyl-terminal domain less|dynamin-1-like protein|dynamin-like protein 4|dynamin-like protein IV|dynamin-related protein 1 |
Position | 12p11.21 |
Gene Type | protein-coding |
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PAH Type |
Description |
PAH | DRP-1-mediated mitotic fission is a cell-cycle checkpoint that can be therapeutically targeted in hyperproliferative disorders such as pulmonary arterial hypertension. |
PAH | DRP-1-mediated mitotic fission is a cell-cycle checkpoint that can be therapeutically targeted in hyperproliferative disorders such as pulmonary arterial hypertension. |
PAH | DRP-1-mediated mitotic fission is a cell-cycle checkpoint that can be therapeutically targeted in hyperproliferative disorders such as pulmonary arterial hypertension. |
| More detail of all Human literatures about DNM1L | |
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Pathways and Diseases |
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Pathway | Bacterial invasion of epithelial cells;KEGG PATHWAY;hsa05100 |
Pathway | Endocytosis;KEGG PATHWAY;hsa04144 |
Pathway | Fc gamma R-mediated phagocytosis;KEGG PATHWAY;hsa04666 |
Pathway | Apoptotic execution phase;PID Reactome;500269 |
Pathway | Apoptosis;Reactome;REACT:578 |
Disease | Leukemia;FunDO |
Disease | Congenital abnormality;FunDO |
Disease | Encephalopahty, lethal, due to defective mitochondrial peroxisomal fission;OMIM |
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External Links |
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Links to Entrez Gene | 10059 |
Links to all GeneRIF Items | 10059 |
Links to iHOP | 10059 |
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Sequence Information |
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Nucleotide Sequence |
>10059 : length: 2100 atggaggcgctaattcctgtcataaacaagctccaggacgtcttcaacacggtgggcgcc gacatcatccagctgcctcaaatcgtcgtagtgggaacgcagagcagcggaaagagctca gtgctagaaagcctggtggggagggacctgcttcccagaggtactggaattgtcacccgg agacctctcattctgcaactggtccatgtttcacaagaagataaacggaaaacaacagga gaagaaaatggggtggaagcagaagaatggggtaaatttcttcacaccaaaaataagctt tacacggattttgatgaaattcgacaagaaattgaaaatgaaacagaaagaatttcagga aataataagggagtaagccctgaaccaattcatcttaagattttttcacccaacgttgtc aatttgacacttgtggatttgccaggaatgaccaaggtgcctgtaggtgatcaacctaag gatattgagcttcaaatcagagagctcattcttcggttcatcagtaatcctaattccatt atcctcgctgtcactgctgctaatacagatatggcaacatcagaggcacttaaaatttca agagaggtagatccagatggtcgcagaaccctagctgtaatcactaaacttgatctcatg gatgcgggtactgatgccatggatgtattgatgggaagggttattccagtcaaacttgga ataattggagtagttaacaggagccagctagatattaacaacaagaagagtgtaactgat tcaatccgtgatgagtatgcttttcttcaaaagaaatatccatctctggccaatagaaat ggaacaaagtatcttgctaggactctaaacaggttactgatgcatcacatcagagattgt ttaccagagttgaaaacaagaataaatgttctagctgctcagtatcagtctcttctaaat agctacggtgaacccgtggatgataaaagtgctactttactccaacttattaccaaattt gccacagaatattgtaacactattgaaggaactgcaaaatatattgaaacttcggagcta tgcggtggtgctagaatttgttatattttccatgagacttttgggcgaaccttagaatct gttgatccacttggtggccttaacactattgacattttgactgccattagaaatgctact ggtcctcgtcctgctttatttgtgcctgaggtttcatttgagttactggtgaagcggcaa atcaaacgtctagaagagcccagcctccgctgtgtggaactggttcatgaggaaatgcaa aggatcattcagcactgtagcaattacagtacacaggaattgttacgatttcctaaactt catgatgccatagttgaagtggtgacttgtcttcttcgtaaaaggttgcctgttacaaat gaaatggtccataacttagtggcaattgaactggcttatatcaacacaaaacatccagac tttgctgatgcttgtgggctaatgaacaataatatagaggaacaaaggagaaacaggcta gccagagaattaccttcagctgtatcacgagacaaggttgcatctggaggtggtggggtt ggagatggtgttcaagaaccaaccacaggcaactggagaggaatgctgaaaacttcaaaa gctgaagagttattagcagaagaaaaatcaaaacccattccaattatgccagccagtcca caaaaaggtcatgccgtgaacctgctagatgtgccagttcctgttgcacgaaaactatct gctcgggaacagcgagattgtgaggttattgaacgactcattaaatcatattttctcatt gtcagaaagaatattcaagacagtgtgccaaaggcagtaatgcattttttggttaatcat gtgaaagacactcttcagagtgagctagtaggccagctgtataaatcatccttattggat gatcttctgacagaatctgaggacatggcacagcgcaggaaagaagcagctgatatgcta aaggcattacaaggagccagtcaaattattgctgaaatccgggagactcatctttggtga |
Protein Sequence |
>10059 : length: 699 MEALIPVINKLQDVFNTVGADIIQLPQIVVVGTQSSGKSSVLESLVGRDLLPRGTGIVTR RPLILQLVHVSQEDKRKTTGEENGVEAEEWGKFLHTKNKLYTDFDEIRQEIENETERISG NNKGVSPEPIHLKIFSPNVVNLTLVDLPGMTKVPVGDQPKDIELQIRELILRFISNPNSI ILAVTAANTDMATSEALKISREVDPDGRRTLAVITKLDLMDAGTDAMDVLMGRVIPVKLG IIGVVNRSQLDINNKKSVTDSIRDEYAFLQKKYPSLANRNGTKYLARTLNRLLMHHIRDC LPELKTRINVLAAQYQSLLNSYGEPVDDKSATLLQLITKFATEYCNTIEGTAKYIETSEL CGGARICYIFHETFGRTLESVDPLGGLNTIDILTAIRNATGPRPALFVPEVSFELLVKRQ IKRLEEPSLRCVELVHEEMQRIIQHCSNYSTQELLRFPKLHDAIVEVVTCLLRKRLPVTN EMVHNLVAIELAYINTKHPDFADACGLMNNNIEEQRRNRLARELPSAVSRDKVASGGGGV GDGVQEPTTGNWRGMLKTSKAEELLAEEKSKPIPIMPASPQKGHAVNLLDVPVPVARKLS AREQRDCEVIERLIKSYFLIVRKNIQDSVPKAVMHFLVNHVKDTLQSELVGQLYKSSLLD DLLTESEDMAQRRKEAADMLKALQGASQIIAEIRETHLW |