| General information | Literature | Expression | Regulation | Variant | Interaction |
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Basic Information |
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|---|---|
Gene ID | 10201 |
Name | NME6 |
Synonym | IPIA-ALPHA|NDK 6|NM23-H6;NME/NM23 nucleoside diphosphate kinase 6;NME6;NME/NM23 nucleoside diphosphate kinase 6 |
Definition | NDP kinase 6|inhibitor of p53-induced apoptosis-alpha|non-metastatic cells 6, protein expressed in (nucleoside-diphosphate kinase)|nucleoside diphosphate kinase 6 |
Position | 3p21 |
Gene Type | protein-coding |
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PAH Type |
Description |
PAH | "We observed linkage evidence in four regions: 3q22 ([median log of the odds (LOD) = 3.43]), 3p12 (median LOD) = 2.35), 2p22 (median LOD = 2.21), and 13q21 (median LOD = 2.09). When used in conjunction with the non-parametric bootstrap, our approach yields high-resolution to identify candidate gene regions containing putative BMPR2-interacting genes. Imputation of the disease model by LOD-score maximization indicates that the 3q22 locus alone predicts most FPAH cases in BMPR2 mutation carriers, providing strong evidence that BMPR2 and the 3q22 locus interact epistatically." |
| More detail of all Human literatures about NME6 | |
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Pathways and Diseases |
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Pathway | salvage pathways of pyrimidine ribonucleotides;BioCyc;PWY0-163 |
Pathway | pyrimidine deoxyribonucleotides de novo biosynthesis;BioCyc;PWY0-166 |
Pathway | pyrimidine ribonucleotides de novo biosynthesis;BioCyc;PWY0-162 |
Pathway | Metabolic pathways;KEGG PATHWAY;hsa01100 |
Pathway | Purine metabolism;KEGG PATHWAY;hsa00230 |
Pathway | Pyrimidine metabolism;KEGG PATHWAY;hsa00240 |
Pathway | pyrimidine ribonucleotides interconversion;BioCyc;PWY-5687 |
Pathway | De novo purine biosynthesis;PANTHER;P02738 |
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External Links |
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Links to Entrez Gene | 10201 |
Links to all GeneRIF Items | 10201 |
Links to iHOP | 10201 |
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Sequence Information |
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Nucleotide Sequence |
>10201 : length: 585 atgacccagaatctggggagtgagatggcctcaatcttgcgaagccctcaggctctccag ctcactctagccctgatcaagcctgacgcagtcgcccatccactgattctggaggctgtt catcagcagattctaagcaacaagttcctgattgtacgaatgagagaactactgtggaga aaggaagattgccagaggttttaccgagagcatgaagggcgttttttctatcagaggctg gtggagttcatggccagcgggccaatccgagcctacatccttgcccacaaggatgccatc cagctctggaggacgctcatgggacccaccagagtgttccgagcacgccatgtggcccca gattctatccgtgggagtttcggcctcactgacacccgcaacaccacccatggttcggac tctgtggtttcagccagcagagagattgcagccttcttccctgacttcagtgaacagcgc tggtatgaggaggaagagccccagttgcgctgtggccctgtgtgctatagcccagaggga ggtgtccactatgtagctggaacaggaggcctaggaccagcctga |
Protein Sequence |
>10201 : length: 194 MTQNLGSEMASILRSPQALQLTLALIKPDAVAHPLILEAVHQQILSNKFLIVRMRELLWR KEDCQRFYREHEGRFFYQRLVEFMASGPIRAYILAHKDAIQLWRTLMGPTRVFRARHVAP DSIRGSFGLTDTRNTTHGSDSVVSASREIAAFFPDFSEQRWYEEEEPQLRCGPVCYSPEG GVHYVAGTGGLGPA |