| General information | Literature | Expression | Regulation | Variant | Interaction |
|
Basic Information |
|
|---|---|
Gene ID | 10911 |
Name | UTS2 |
Synonym | PRO1068|U-II|UCN2|UII;urotensin 2;UTS2;urotensin 2 |
Definition | prepro U-II|urotensin II|urotensin-2 |
Position | 1p36 |
Gene Type | protein-coding |
|
PAH Type |
Description |
PH | The expression of U II and Uts2R in right ventricle arteries and right ventricle myocytes increases significantly during the formation of pulmonary hypertension and right ventricle hypertrophy in rats chronically exposed to hypoxia-hypercapnia. |
PH | Urotensin II was expressed in the lung of pulmonary hypertension patients with congenital heart disease. |
| More detail of all Rat literatures about UTS2 | |
|
Pathways and Diseases |
|
Pathway | Signaling by GPCR;Reactome;REACT:14797 |
Disease | Hypertension;FunDO |
Disease | diabetes, type 2;GAD |
Disease | hypertension;GAD |
Disease | Diabetes mellitus;FunDO |
Disease | Cardiovascular disease;FunDO |
Disease | CARDIOVASCULAR;GAD |
Disease | diabetes, gestational;GAD |
Disease | Hemolytic-Uremic syndrome;FunDO |
Disease | Adrenal gland tumor;FunDO |
Disease | METABOLIC;GAD |
Disease | Kidney disease;FunDO |
Disease | myocardial infarct;GAD |
Disease | glucose tolerance insulin;GAD |
|
External Links |
|
Links to Entrez Gene | 10911 |
Links to all GeneRIF Items | 10911 |
Links to iHOP | 10911 |
|
Sequence Information |
|
Nucleotide Sequence |
>10911 : length: 375 atgtataagctggcctcctgctgtttgcttttcataggattcttaaatcctctcttatct cttcctctccttgactccagggaaatatcctttcaactctcagcacctcatgaagacgcg cgcttaactccggaggagctagaaagagcttcccttctacagatactgccagagatgctg ggtgcagaaagaggggatattctcaggaaagcagactcaagtaccaacatttttaaccca agaggaaatttgagaaagtttcaggatttctctggacaagatcctaacattttactgagt catcttttggccagaatctggaaaccatacaagaaacgtgagactcctgattgcttctgg aaatactgtgtctga |
Protein Sequence |
>10911 : length: 124 MYKLASCCLLFIGFLNPLLSLPLLDSREISFQLSAPHEDARLTPEELERASLLQILPEML GAERGDILRKADSSTNIFNPRGNLRKFQDFSGQDPNILLSHLLARIWKPYKKRETPDCFW KYCV |