Pulmonary Arterial Hypertension KnowledgeBase (PAHKB)
PAHKB
Pulmonary Arterial Hypertension KnowledgeBase
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

10956

Name

OS9

Synonym

ERLEC2|OS-9;osteosarcoma amplified 9, endoplasmic reticulum lectin;OS9;osteosarcoma amplified 9, endoplasmic reticulum lectin

Definition

amplified in osteosarcoma 9|endoplasmic reticulum lectin 2|erlectin 2|osteosarcoma amplified 9, endoplasmic reticulum associated protein|protein OS-9

Position

12q13

Gene Type

protein-coding

PAH Type

Description

HPH

"HIF-1alpha, procollagen-proline dioxygenases and OS-9 are all involved in the pathogenesis of hypoxic pulmonary hypertension in rats."
More detail of all Rat literatures about OS9

Pathways and Diseases

Pathway

Protein processing in endoplasmic reticulum;KEGG PATHWAY;hsa04141

Disease

Melanoma;FunDO

Disease

Myopathy;FunDO

Disease

Encephalopathies;FunDO

External Links

Links to Entrez Gene

10956

Links to all GeneRIF Items

10956

Links to iHOP

10956

Sequence Information

Nucleotide Sequence

>10956 : length: 1839
atggcggcggaaacgctgctgtccagtttgttaggactgctgcttctgggactcctgtta
cccgcaagtctgaccggcggtgtcgggagcctgaacctggaggagctgagtgagatgcgt
tatgggatcgagatcctgccgttgcctgtcatgggagggcagagccaatcttcggacgtg
gtgattgtctcctctaagtacaaacagcgctatgagtgtcgcctgccagctggagctatt
cacttccagcgtgaaagggaggaggaaacacctgcttaccaagggcctgggatccctgag
ttgttgagcccaatgagagatgctccctgcttgctgaagacaaaggactggtggacatat
gaattctgttatggacgccacatccagcaataccacatggaagattcagagatcaaaggt
gaagtcctctatctcggctactaccaatcagccttcgactgggatgatgaaacagccaag
gcctccaagcagcatcgtcttaaacgctaccacagccagacctatggcaatgggtccaag
tgcgaccttaatgggaggccccgggaggccgaggttcggttcctctgtgacgagggtgca
ggtatctctggggactacatcgatcgcgtggacgagcccttgtcctgctcttatgtgctg
accattcgcactcctcggctctgcccccaccctctcctccggcccccacccagtgctgca
ccgcaggccatcctctgtcacccttccctacagcctgaggagtacatggcctacgttcag
aggcaagccgactcaaagcagtatggagataaaatcatagaggagctgcaagatctaggc
ccccaagtgtggagtgagaccaagtctggggtggcaccccaaaagatggcaggtgcgagc
ccgaccaaggatgacagtaaggactcagatttctggaagatgcttaatgagccagaggac
caggccccaggaggggaggaggtgccggctgaggagcaggacccaagccctgaggcagca
gattcagcttctggtgctcccaatgattttcagaacaacgtgcaggtcaaagtcattcga
agccctgcggatttgattcgattcatagaggagctgaaaggtggaacaaaaaaggggaag
ccaaatataggccaagagcagcctgtggatgatgctgcagaagtccctcagagggaacca
gagaaggaaaggggtgatccagaacggcagagagagatggaagaagaggaggatgaggat
gaggatgaggatgaagatgaggatgaacggcagttactgggagaatttgagaaggaactg
gaagggatcctgcttccgtcagaccgagaccggctccgttcggaggtgaaggctggcatg
gagcgggaactggaaaacatcatccaggagacagagaaagagctggacccagatgggctg
aagaaggagtcagagcgggatcgggcaatgctggctctcacatccactctcaacaaactc
atcaaaagactggaggaaaaacagagtccagagctggtgaagaagcacaagaaaaagagg
gttgtccccaaaaagcctcccccatcaccccaacctacagggaaaattgagatcaaaatt
gtccgcccatgggctgaagggactgaagagggtgcacgttggctgactgatgaggacacg
agaaacctcaaggagatcttcttcaatatcttggtgccgggagctgaagaggcccagaag
gaacgccagcggcagaaagagctggagagcaattaccgccgggtgtggggctctccaggt
ggggagggcacaggggacctggacgaatttgacttctga

Protein Sequence

>10956 : length: 612
MAAETLLSSLLGLLLLGLLLPASLTGGVGSLNLEELSEMRYGIEILPLPVMGGQSQSSDV
VIVSSKYKQRYECRLPAGAIHFQREREEETPAYQGPGIPELLSPMRDAPCLLKTKDWWTY
EFCYGRHIQQYHMEDSEIKGEVLYLGYYQSAFDWDDETAKASKQHRLKRYHSQTYGNGSK
CDLNGRPREAEVRFLCDEGAGISGDYIDRVDEPLSCSYVLTIRTPRLCPHPLLRPPPSAA
PQAILCHPSLQPEEYMAYVQRQADSKQYGDKIIEELQDLGPQVWSETKSGVAPQKMAGAS
PTKDDSKDSDFWKMLNEPEDQAPGGEEVPAEEQDPSPEAADSASGAPNDFQNNVQVKVIR
SPADLIRFIEELKGGTKKGKPNIGQEQPVDDAAEVPQREPEKERGDPERQREMEEEEDED
EDEDEDEDERQLLGEFEKELEGILLPSDRDRLRSEVKAGMERELENIIQETEKELDPDGL
KKESERDRAMLALTSTLNKLIKRLEEKQSPELVKKHKKKRVVPKKPPPSPQPTGKIEIKI
VRPWAEGTEEGARWLTDEDTRNLKEIFFNILVPGAEEAQKERQRQKELESNYRRVWGSPG
GEGTGDLDEFDF



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