Pulmonary Arterial Hypertension KnowledgeBase (PAHKB)
PAHKB
Pulmonary Arterial Hypertension KnowledgeBase
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

1236

Name

CCR7

Synonym

BLR2|CD197|CDw197|CMKBR7|EBI1;chemokine (C-C motif) receptor 7;CCR7;chemokine (C-C motif) receptor 7

Definition

C-C CKR-7|C-C chemokine receptor type 7|CC chemokine receptor 7|CC-CKR-7|CCR-7|EBV-induced G protein-coupled receptor 1|EBV-induced G-protein coupled receptor 1|Epstein-Barr virus induced G-protein coupled receptor|Epstein-Barr virus induced gene 1|MIP-3

Position

17q12-q21.2

Gene Type

protein-coding

PAH Type

Description

PAH

Lack of CCR7 induces pulmonary hypertension involving perivascular leukocyte infiltration and inflammation.
More detail of all Mouse literatures about CCR7

Pathways and Diseases

Pathway

Signaling by GPCR;Reactome;REACT:14797

Pathway

Cytokine-cytokine receptor interaction;KEGG PATHWAY;hsa04060

Pathway

Chemokine receptors bind chemokines;PID Reactome;500406

Pathway

Inflammation mediated by chemokine and cytokine signaling pathway;PANTHER;P00031

Pathway

Chemokine signaling pathway;KEGG PATHWAY;hsa04062

External Links

Links to Entrez Gene

1236

Links to all GeneRIF Items

1236

Links to iHOP

1236

Sequence Information

Nucleotide Sequence

>1236 : length: 1137
atggacctggggaaaccaatgaaaagcgtgctggtggtggctctccttgtcattttccag
gtatgcctgtgtcaagatgaggtcacggacgattacatcggagacaacaccacagtggac
tacactttgttcgagtctttgtgctccaagaaggacgtgcggaactttaaagcctggttc
ctccctatcatgtactccatcatttgtttcgtgggcctactgggcaatgggctggtcgtg
ttgacctatatctatttcaagaggctcaagaccatgaccgatacctacctgctcaacctg
gcggtggcagacatcctcttcctcctgacccttcccttctgggcctacagcgcggccaag
tcctgggtcttcggtgtccacttttgcaagctcatctttgccatctacaagatgagcttc
ttcagtggcatgctcctacttctttgcatcagcattgaccgctacgtggccatcgtccag
gctgtctcagctcaccgccaccgtgcccgcgtccttctcatcagcaagctgtcctgtgtg
ggcatctggatactagccacagtgctctccatcccagagctcctgtacagtgacctccag
aggagcagcagtgagcaagcgatgcgatgctctctcatcacagagcatgtggaggccttt
atcaccatccaggtggcccagatggtgatcggctttctggtccccctgctggccatgagc
ttctgttaccttgtcatcatccgcaccctgctccaggcacgcaactttgagcgcaacaag
gccatcaaggtgatcatcgctgtggtcgtggtcttcatagtcttccagctgccctacaat
ggggtggtcctggcccagacggtggccaacttcaacatcaccagtagcacctgtgagctc
agtaagcaactcaacatcgcctacgacgtcacctacagcctggcctgcgtccgctgctgc
gtcaaccctttcttgtacgccttcatcggcgtcaagttccgcaacgatctcttcaagctc
ttcaaggacctgggctgcctcagccaggagcagctccggcagtggtcttcctgtcggcac
atccggcgctcctccatgagtgtggaggccgagaccaccaccaccttctccccatag

Protein Sequence

>1236 : length: 378
MDLGKPMKSVLVVALLVIFQVCLCQDEVTDDYIGDNTTVDYTLFESLCSKKDVRNFKAWF
LPIMYSIICFVGLLGNGLVVLTYIYFKRLKTMTDTYLLNLAVADILFLLTLPFWAYSAAK
SWVFGVHFCKLIFAIYKMSFFSGMLLLLCISIDRYVAIVQAVSAHRHRARVLLISKLSCV
GIWILATVLSIPELLYSDLQRSSSEQAMRCSLITEHVEAFITIQVAQMVIGFLVPLLAMS
FCYLVIIRTLLQARNFERNKAIKVIIAVVVVFIVFQLPYNGVVLAQTVANFNITSSTCEL
SKQLNIAYDVTYSLACVRCCVNPFLYAFIGVKFRNDLFKLFKDLGCLSQEQLRQWSSCRH
IRRSSMSVEAETTTTFSP



')