| General information | Literature | Expression | Regulation | Variant | Interaction |
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Basic Information |
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|---|---|
Gene ID | 1361 |
Name | CPB2 |
Synonym | CPU|PCPB|TAFI;carboxypeptidase B2 (plasma);CPB2;carboxypeptidase B2 (plasma) |
Definition | carboxypeptidase B-like protein|carboxypeptidase B2|carboxypeptidase B2 (plasma, carboxypeptidase U)|carboxypeptidase R|thrombin-activable fibrinolysis inhibitor|thrombin-activatable fibrinolysis inhibitor |
Position | 13q14.11 |
Gene Type | protein-coding |
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PAH Type |
Description |
PH | Pulmonary hypertension is ameliorated in mice deficient in thrombin-activatable fibrinolysis inhibitor. |
| More detail of all Mouse literatures about CPB2 | |
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Pathways and Diseases |
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Pathway | Complement and coagulation cascades;KEGG PATHWAY;hsa04610 |
Pathway | fibrinolysis pathway;PID BioCarta;100164 |
Pathway | Pancreatic secretion;KEGG PATHWAY;hsa04972 |
Pathway | Plasminogen activating cascade;PANTHER;P00050 |
Pathway | Protein digestion and absorption;KEGG PATHWAY;hsa04974 |
Disease | HEMATOLOGICAL;GAD |
Disease | angina;GAD |
Disease | thrombin-activatable fibrinolysis inhibitor levels;GAD |
Disease | CARDIOVASCULAR;GAD |
Disease | blood pressure;GAD |
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External Links |
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Links to Entrez Gene | 1361 |
Links to all GeneRIF Items | 1361 |
Links to iHOP | 1361 |
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Sequence Information |
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Nucleotide Sequence |
>1361 : length: 1272 atgaagctttgcagccttgcagtccttgtacccattgttctcttctgtgagcagcatgtc ttcgcgtttcagagtggccaagttctagctgctcttcctagaacctctaggcaagttcaa gttctacagaatcttactacaacatatgagattgttctctggcagccggtaacagctgac cttattgtgaagaaaaaacaagtccatttttttgtaaatgcatctgatgtcgacaatgtg aaagcccatttaaatgtgagcggaattccatgcagtgtcttgctggcagatgtggaagat cttattcaacagcagatttccaacgacacagtcagcccccgagcctccgcatcgtactat gaacagtatcactcactaaatgaaatctattcttggatagaatttataactgagaggcat cctgatatgcttacaaaaatccacattggatcctcatttgagaagtacccactctatgtt ttaaaggtttctggaaaagaacaagcagccaaaaatgccatatggattgactgtggaatc catgccagagaatggatctctcctgctttctgcttgtggttcataggccatataactcaa ttctatgggataatagggcaatataccaatctcctgaggcttgtggatttctatgttatg ccagtggttaatgtggatggttatgactactcatggaaaaagaatcgaatgtggagaaag aaccgttctttctatgcgaacaatcattgcatcggaacagacctgaataggaactttgct tccaaacactggtgtgaggaaggtgcatccagttcctcatgctcggaaacctactgtgga ctttatcctgagtcagaaccagaagtgaaggcagtggctagtttcttgagaagaaatatc aaccagattaaagcatacatcagcatgcattcatactcccagcatatagtgtttccatat tcctatacacgaagtaaaagcaaagaccatgaggaactgtctctagtagccagtgaagca gttcgtgctattgagaaaactagtaaaaataccaggtatacacatggccatggctcagaa accttatacctagctcctggaggtggggacgattggatctatgatttgggcatcaaatat tcgtttacaattgaacttcgagatacgggcacatacggattcttgctgccggagcgttac atcaaacccacctgtagagaagcttttgccgctgtctctaaaatagcttggcatgtcatt aggaatgtttaa |
Protein Sequence |
>1361 : length: 423 MKLCSLAVLVPIVLFCEQHVFAFQSGQVLAALPRTSRQVQVLQNLTTTYEIVLWQPVTAD LIVKKKQVHFFVNASDVDNVKAHLNVSGIPCSVLLADVEDLIQQQISNDTVSPRASASYY EQYHSLNEIYSWIEFITERHPDMLTKIHIGSSFEKYPLYVLKVSGKEQAAKNAIWIDCGI HAREWISPAFCLWFIGHITQFYGIIGQYTNLLRLVDFYVMPVVNVDGYDYSWKKNRMWRK NRSFYANNHCIGTDLNRNFASKHWCEEGASSSSCSETYCGLYPESEPEVKAVASFLRRNI NQIKAYISMHSYSQHIVFPYSYTRSKSKDHEELSLVASEAVRAIEKTSKNTRYTHGHGSE TLYLAPGGGDDWIYDLGIKYSFTIELRDTGTYGFLLPERYIKPTCREAFAAVSKIAWHVI RNV |