| General information | Literature | Expression | Regulation | Variant | Interaction |
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Basic Information |
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|---|---|
Gene ID | 1491 |
Name | CTH |
Synonym | -;cystathionase (cystathionine gamma-lyase);CTH;cystathionase (cystathionine gamma-lyase) |
Definition | cystathionine gamma-lyase|cysteine desulfhydrase|cysteine-protein sulfhydrase|gamma-cystathionase|homoserine deaminase|homoserine dehydratase |
Position | 1p31.1 |
Gene Type | protein-coding |
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PAH Type |
Description |
PH | L-Arginine reverses the down-regulation of CSE/H2S system in high pulmonary blood flow-induced pulmonary hypertension. |
| More detail of all Rat literatures about CTH | |
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Pathways and Diseases |
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Pathway | cysteine biosynthesis/homocysteine degradation;BioCyc;HOMOCYSDEGR-PWY |
Pathway | Selenoamino acid metabolism;KEGG PATHWAY;hsa00450 |
Pathway | L-cysteine degradation II;BioCyc;LCYSDEG-PWY |
Pathway | Glycine, serine and threonine metabolism;KEGG PATHWAY;hsa00260 |
Pathway | Nitrogen metabolism;KEGG PATHWAY;hsa00910 |
Pathway | cysteine biosynthesis III (mammalia);BioCyc;PWY-6292 |
Pathway | Metabolic pathways;KEGG PATHWAY;hsa01100 |
Pathway | Cysteine and methionine metabolism;KEGG PATHWAY;hsa00270 |
Pathway | superpathway of methionine degradation;BioCyc;PWY-5328 |
Disease | Hypertension;FunDO |
Disease | Cystathioninuria;OMIM |
Disease | Homocysteine, total plasma, elevated;OMIM |
Disease | Genetic disorders;KEGG DISEASE |
Disease | Inherited disorders of amino acid metabolism;KEGG DISEASE |
Disease | Cystathioninuria;KEGG DISEASE;H00182 |
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External Links |
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Links to Entrez Gene | 1491 |
Links to all GeneRIF Items | 1491 |
Links to iHOP | 1491 |
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Sequence Information |
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Nucleotide Sequence |
>1491 : length: 1122 atgcaggaaaaagacgcctcctcacaaggtttcctgccacacttccaacatttcgccacg caggcgatccatgtgggccaggatccagagcaatggacctccagggctgtagtgcccccc atctcactgtccaccacgttcaagcaaggggcgcctggccagcactcgggttttgaatat agccgttctggaaatcccactaggaattgccttgaaaaagcagtggcagcactggatggg gctaagtactgtacaaacaggtacttcaggcaagtggcatctgaatttggattaaagatt tcttttgttgattgttccaaaatcaaattactagaggcagcaattacaccagaaaccaag cttgtttggatcgaaacccccacaaaccccacccagaaggtgattgacattgaaggctgt gcacatattgtccataagcatggagacattattttggtcgtggataacacttttatgtca ccatatttccagcgccctttggctctgggagctgatatttctatgtattctgcaacaaaa tacatgaatggccacagtgatgttgtaatgggcctggtgtctgttaattgtgaaagcctt cataatagacttcgtttcttgcaaaactctcttggagcagttccatctcctattgattgt tacctctgcaatcgaggtctgaagactctacatgtccgaatggaaaagcatttcaaaaac ggaatggcagttgcccagttcctggaatctaatccttgggtagaaaaggttatttatcct gggctgccctctcatccacagcatgagttggtgaagcgtcagtgtacaggttgtacaggg atggtcaccttttatattaagggcactcttcagcatgctgagattttcctcaagaaccta aagctatttactctggccgagagcttgggaggattcgaaagccttgctgagcttccggca atcatgactcatgcatcagttcttaagaatgacagagatgtccttggaattagtgacaca ctgattcgactttctgtgggcttagaggatgaggaagacctactggaagatctagatcaa gctttgaaggcagcacaccctccaagtggaagtcacagctag |
Protein Sequence |
>1491 : length: 373 MQEKDASSQGFLPHFQHFATQAIHVGQDPEQWTSRAVVPPISLSTTFKQGAPGQHSGFEY SRSGNPTRNCLEKAVAALDGAKYCTNRYFRQVASEFGLKISFVDCSKIKLLEAAITPETK LVWIETPTNPTQKVIDIEGCAHIVHKHGDIILVVDNTFMSPYFQRPLALGADISMYSATK YMNGHSDVVMGLVSVNCESLHNRLRFLQNSLGAVPSPIDCYLCNRGLKTLHVRMEKHFKN GMAVAQFLESNPWVEKVIYPGLPSHPQHELVKRQCTGCTGMVTFYIKGTLQHAEIFLKNL KLFTLAESLGGFESLAELPAIMTHASVLKNDRDVLGISDTLIRLSVGLEDEEDLLEDLDQ ALKAAHPPSGSHS |