| General information | Literature | Expression | Regulation | Variant | Interaction |
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Basic Information |
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|---|---|
Gene ID | 1605 |
Name | DAG1 |
Synonym | 156DAG|A3a|AGRNR|DAG|MDDGC7|MDDGC9;dystroglycan 1 (dystrophin-associated glycoprotein 1);DAG1;dystroglycan 1 (dystrophin-associated glycoprotein 1) |
Definition | dystroglycan |
Position | 3p21 |
Gene Type | protein-coding |
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PAH Type |
Description |
PAH | "We observed linkage evidence in four regions: 3q22 ([median log of the odds (LOD) = 3.43]), 3p12 (median LOD) = 2.35), 2p22 (median LOD = 2.21), and 13q21 (median LOD = 2.09). When used in conjunction with the non-parametric bootstrap, our approach yields high-resolution to identify candidate gene regions containing putative BMPR2-interacting genes. Imputation of the disease model by LOD-score maximization indicates that the 3q22 locus alone predicts most FPAH cases in BMPR2 mutation carriers, providing strong evidence that BMPR2 and the 3q22 locus interact epistatically." |
| More detail of all Human literatures about DAG1 | |
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Pathways and Diseases |
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Pathway | agrin in postsynaptic differentiation;PID BioCarta;100252 |
Pathway | Arrhythmogenic right ventricular cardiomyopathy (ARVC);KEGG PATHWAY;hsa05412 |
Pathway | Viral myocarditis;KEGG PATHWAY;hsa05416 |
Pathway | Dilated cardiomyopathy;KEGG PATHWAY;hsa05414 |
Pathway | Hypertrophic cardiomyopathy (HCM);KEGG PATHWAY;hsa05410 |
Pathway | ECM-receptor interaction;KEGG PATHWAY;hsa04512 |
Disease | bronchopulmonary dysplasia;GAD |
Disease | Cancer;FunDO |
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External Links |
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Links to Entrez Gene | 1605 |
Links to all GeneRIF Items | 1605 |
Links to iHOP | 1605 |
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Sequence Information |
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Nucleotide Sequence |
>1605 : length: 2688 atgaggatgtctgtgggcctctcgctgctgctgcccctctgggggaggacctttctcctc ctgctctctgtggttatggctcagtcccactggcccagtgaaccctcagaggctgtcagg gactgggaaaaccagcttgaggcatccatgcactcagtgctctcagacctccacgaggct gttcccacagtggttggcattcctgatggcacggctgtcgtcgggcgctcatttcgagtg accattccaacagatttgattgcctccagtggagatatcatcaaggtatcagcggcaggg aaggaggctttgccatcttggctgcactgggactcacagagccacaccctggagggcctc ccccttgacactgataagggtgtgcattacatttcagtgagcgctacacggctgggggcc aacgggagccacatcccccagacctccagtgtgttctccatcgaggtctaccctgaagac cacagtgagctgcagtcggtgaggacagcctccccagaccctggtgaggtggtatcatct gcctgtgctgcggatgaacctgtgactgttttgacggtgattttggatgccgacctcacc aagatgaccccaaagcaaaggattgacctcctgcacaggatgcggagcttctcagaagta gagcttcacaacatgaaattagtgccggtggtgaataacagactatttgacatgtcggcc ttcatggctggcccgggaaatgcaaaaaaggtggtggagaatggggcccttctctcctgg aagctgggctgctccctgaaccagaacagtgtgcctgacattcatggtgtagaggcccct gccagggagggcgcaatgtctgctcagcttggctaccctgtggtgggttggcacatcgcc aataagaagccccctcttcccaaacgcgtccggaggcagatccatgctacacccacacct gtcactgccattgggcccccaaccacggctatccaggagcccccatccaggatcgtgcca acccccacatctccagccattgctcctccaacagagaccatggctcctccagtcagggat cctgttcctgggaaacccacggtcaccatccggactcgaggcgccattattcaaacccca accctaggccccatccagcctactcgggtgtcagaagctggcaccacagttcctggccag attcgcccaacgatgaccattcctggctatgtggagcctactgcagttgctacccctccc acaaccaccaccaagaagccacgagtatccacaccaaaaccagcaacgccttcaactgac tccaccaccaccacgactcgcaggccaaccaagaaaccacggacaccccggccagtgccc cgggtcaccaccaaagtttccatcaccagattggaaactgcctcaccgcctactcgtatt cgcaccaccaccagtggagtgccccgtggcggagaacccaaccagcgcccagagctcaag aaccatattgacagggtagatgcctgggttggcacctactttgaggtgaagatcccgtca gacactttctatgaccatgaggacaccaccactgacaagctgaagctgaccctgaaactg cgggagcagcagctggtgggcgagaagtcctgggtacagttcaacagcaacagccagctc atgtatggccttcccgacagcagccacgtgggcaaacacgagtatttcatgcatgccaca gacaaggggggcctgtcggctgtggatgccttcgagatccacgtccacaggcgcccccaa ggggatagggctcctgcaaggttcaaggccaagtttgtgggtgacccggcactggtgttg aatgacatccacaagaagattgccttggtaaagaaactggccttcgcctttggagaccga aactgtagcaccatcaccctgcagaatatcacccggggctccatcgtggtggaatggacc aacaacacactgcccttggagccctgccccaaggagcagatcgctgggctgagccgccgg atcgctgaggatgatggaaaacctcggcctgccttctccaacgccctagagcctgacttt aaggccacaagcatcactgtgacgggctctggcagttgtcggcacctacagtttatccct gtggtaccacccaggagagtgccctcagaggcgccgcccacagaagtgcctgacagggac cctgagaagagcagtgaggatgatgtctacctgcacacagtcattccggccgtggtggtc gcagccatcctgctcattgctggcatcattgccatgatctgctaccgcaagaagcggaag ggcaagcttacccttgaggaccaggccaccttcatcaagaagggggtgcctatcatcttt gcagacgaactggacgactccaagcccccaccctcctccagcatgccactcattctgcag gaggagaaggctcccctaccccctcctgagtaccccaaccagagtgtgcccgagaccact cctctgaaccaggacaccatgggagagtacacgcccctgcgggatgaggatcccaatgcg cctccctaccagcccccaccgcccttcacagcacccatggagggcaagggctcccgtccc aagaacatgaccccataccggtcacctcctccctatgtcccaccttaa |
Protein Sequence |
>1605 : length: 895 MRMSVGLSLLLPLWGRTFLLLLSVVMAQSHWPSEPSEAVRDWENQLEASMHSVLSDLHEA VPTVVGIPDGTAVVGRSFRVTIPTDLIASSGDIIKVSAAGKEALPSWLHWDSQSHTLEGL PLDTDKGVHYISVSATRLGANGSHIPQTSSVFSIEVYPEDHSELQSVRTASPDPGEVVSS ACAADEPVTVLTVILDADLTKMTPKQRIDLLHRMRSFSEVELHNMKLVPVVNNRLFDMSA FMAGPGNAKKVVENGALLSWKLGCSLNQNSVPDIHGVEAPAREGAMSAQLGYPVVGWHIA NKKPPLPKRVRRQIHATPTPVTAIGPPTTAIQEPPSRIVPTPTSPAIAPPTETMAPPVRD PVPGKPTVTIRTRGAIIQTPTLGPIQPTRVSEAGTTVPGQIRPTMTIPGYVEPTAVATPP TTTTKKPRVSTPKPATPSTDSTTTTTRRPTKKPRTPRPVPRVTTKVSITRLETASPPTRI RTTTSGVPRGGEPNQRPELKNHIDRVDAWVGTYFEVKIPSDTFYDHEDTTTDKLKLTLKL REQQLVGEKSWVQFNSNSQLMYGLPDSSHVGKHEYFMHATDKGGLSAVDAFEIHVHRRPQ GDRAPARFKAKFVGDPALVLNDIHKKIALVKKLAFAFGDRNCSTITLQNITRGSIVVEWT NNTLPLEPCPKEQIAGLSRRIAEDDGKPRPAFSNALEPDFKATSITVTGSGSCRHLQFIP VVPPRRVPSEAPPTEVPDRDPEKSSEDDVYLHTVIPAVVVAAILLIAGIIAMICYRKKRK GKLTLEDQATFIKKGVPIIFADELDDSKPPPSSSMPLILQEEKAPLPPPEYPNQSVPETT PLNQDTMGEYTPLRDEDPNAPPYQPPPPFTAPMEGKGSRPKNMTPYRSPPPYVPP |