| General information | Literature | Expression | Regulation | Variant | Interaction |
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Basic Information |
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|---|---|
Gene ID | 1908 |
Name | EDN3 |
Synonym | ET-3|ET3|HSCR4|PPET3|WS4B;endothelin 3;EDN3;endothelin 3 |
Definition | endothelin-3|preproendothelin-3 |
Position | 20q13.2-q13.3 |
Gene Type | protein-coding |
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PAH Type |
Description |
PAH | Endothelin-3-dependent pulmonary vasoconstriction in monocrotaline-induced pulmonary arterial hypertension. |
| More detail of all Rat literatures about EDN3 | |
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Pathways and Diseases |
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Pathway | Endothelins;PID Curated;200004 |
Pathway | Endothelin signaling pathway;PANTHER;P00019 |
Pathway | Signaling by GPCR;Reactome;REACT:14797 |
Disease | hypertension;GAD |
Disease | Waardenburg syndrome, type 4B;OMIM |
Disease | CARDIOVASCULAR;GAD |
Disease | Hirschsprung disease, susceptibility to, 4;OMIM |
Disease | Melanoma;FunDO |
Disease | Central hypoventilation syndrome, congenital;OMIM |
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External Links |
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Links to Entrez Gene | 1908 |
Links to all GeneRIF Items | 1908 |
Links to iHOP | 1908 |
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Sequence Information |
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Nucleotide Sequence |
>1908 : length: 717 atggagccggggctgtggctccttttcgggctcacagtgacctccgccgcaggattcgtg ccttgctcccagtctggggatgctggcaggcgcggcgtgtcccaggcccccactgcagcc agatctgagggggactgtgaagagactgtggctggccctggcgaggagactgtggctggc cctggcgaggggactgtggccccgacagcactgcagggtccaagccctggaagccctggg caggagcaggcggccgagggggcccctgagcaccaccgatccaggcgctgcacgtgcttc acctacaaggacaaggagtgtgtctactattgccacctggacatcatttggatcaacact cccgaacagacggtgccctatggactgtccaactacagaggaagcttccggggcaagagg tctgcggggccacttccagggaatctgcagctctcacatcggccacacttgcgctgcgct tgtgtggggagatatgacaaggcctgcctgcacttttgcacccaaactctggacgtcagc agtaattcaaggacggcagaaaaaacagacaaagaagaggaagggaaggttgaagtcaag gaccaacaaagcaagcaggctttagacctccaccatccaaagctcatgcccggcagtgga ctcgccctcgctccatctacctgcccccgctgcctctttcaggaaggagccccttag |
Protein Sequence |
>1908 : length: 238 MEPGLWLLFGLTVTSAAGFVPCSQSGDAGRRGVSQAPTAARSEGDCEETVAGPGEETVAG PGEGTVAPTALQGPSPGSPGQEQAAEGAPEHHRSRRCTCFTYKDKECVYYCHLDIIWINT PEQTVPYGLSNYRGSFRGKRSAGPLPGNLQLSHRPHLRCACVGRYDKACLHFCTQTLDVS SNSRTAEKTDKEEEGKVEVKDQQSKQALDLHHPKLMPGSGLALAPSTCPRCLFQEGAP |