| General information | Literature | Expression | Regulation | Variant | Interaction |
|
Basic Information |
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|---|---|
Gene ID | 259236 |
Name | TMIE |
Synonym | DFNB6;transmembrane inner ear;TMIE;transmembrane inner ear |
Definition | transmembrane inner ear expressed protein|transmembrane inner ear protein |
Position | 3p21 |
Gene Type | protein-coding |
|
PAH Type |
Description |
PAH | "We observed linkage evidence in four regions: 3q22 ([median log of the odds (LOD) = 3.43]), 3p12 (median LOD) = 2.35), 2p22 (median LOD = 2.21), and 13q21 (median LOD = 2.09). When used in conjunction with the non-parametric bootstrap, our approach yields high-resolution to identify candidate gene regions containing putative BMPR2-interacting genes. Imputation of the disease model by LOD-score maximization indicates that the 3q22 locus alone predicts most FPAH cases in BMPR2 mutation carriers, providing strong evidence that BMPR2 and the 3q22 locus interact epistatically." |
| More detail of all Human literatures about TMIE | |
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External Links |
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Links to Entrez Gene | 259236 |
Links to all GeneRIF Items | 259236 |
Links to iHOP | 259236 |
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Sequence Information |
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Nucleotide Sequence |
>259236 : length: 471 atggcggggtggccgggcgcgggtcccctctgcgtgctgggcggcgccgcactcggggtg tgcctcgcgggggttgccgggcagctggtggagcccagcacggccccacccaagcccaag ccgcctccgctgaccaaggagacagtggtgttctgggacatgcgcctgtggcacgtggtg ggcatcttttcgctcttcgtgttgtccatcatcatcacgctgtgctgtgtcttcaactgt cgtgtgccacggacccggaaggagatcgaagcccggtacctgcagcgaaaggcagccaag atgtacacagacaagctggagactgtgccacccctcaatgagctcacagaagtcccagga gaggataagaagaagaagaagaagaagaagaaggacagtgtggacacagtggccatcaaa gtagaggaggatgagaagaatgaggccaagaagaagaaaggagagaaatga |
Protein Sequence |
>259236 : length: 156 MAGWPGAGPLCVLGGAALGVCLAGVAGQLVEPSTAPPKPKPPPLTKETVVFWDMRLWHVV GIFSLFVLSIIITLCCVFNCRVPRTRKEIEARYLQRKAAKMYTDKLETVPPLNELTEVPG EDKKKKKKKKKDSVDTVAIKVEEDEKNEAKKKKGEK |