| General information | Literature | Expression | Regulation | Variant | Interaction |
|
Basic Information |
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|---|---|
Gene ID | 284 |
Name | ANGPT1 |
Synonym | AGP1|AGPT|ANG1;angiopoietin 1;ANGPT1;angiopoietin 1 |
Definition | ANG-1|angiopoietin-1 |
Position | 8q23.1 |
Gene Type | protein-coding |
|
PAH Type |
Description |
PAH | Angiopoietin/Tie2 pathway influences smooth muscle hyperplasia in idiopathic pulmonary hypertension. |
PH | "A new animal model for pulmonary hypertension based on the overexpression of a single gene, angiopoietin-1." |
PH | Temporal changes of angiopoietins and Tie2 expression in rat lungs after monocrotaline-induced pulmonary hypertension. |
PH | Demonstrate a negative correlation between serum Ang-1 levels and the degree of pulmonary hypertension due to mitral stenosis. |
| More detail of all Human literatures about ANGPT1 | |
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Pathways and Diseases |
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Pathway | Angiopoietin receptor Tie2-mediated signaling;PID Curated;200066 |
Pathway | Hemostasis;Reactome;REACT:604 |
Pathway | Tie2 Signaling;PID Reactome;500306 |
Pathway | Angiogenesis;PANTHER;P00005 |
Disease | Ischemia;FunDO |
Disease | Diabetes mellitus;FunDO |
Disease | Cardiovascular disease;FunDO |
Disease | Rheumatoid arthritis;FunDO |
Disease | Asthma;FunDO |
Disease | Cancer;FunDO |
Disease | Systemic infection;FunDO |
Disease | Endometriosis;FunDO |
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External Links |
|
Links to Entrez Gene | 284 |
Links to all GeneRIF Items | 284 |
Links to iHOP | 284 |
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Sequence Information |
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Nucleotide Sequence |
>284 : length: 1497 atgacagttttcctttcctttgctttcctcgctgccattctgactcacatagggtgcagc aatcagcgccgaagtccagaaaacagtgggagaagatataaccggattcaacatgggcaa tgtgcctacactttcattcttccagaacacgatggcaactgtcgtgagagtacgacagac cagtacaacacaaacgctctgcagagagatgctccacacgtggaaccggatttctcttcc cagaaacttcaacatctggaacatgtgatggaaaattatactcagtggctgcaaaaactt gagaattacattgtggaaaacatgaagtcggagatggcccagatacagcagaatgcagtt cagaaccacacggctaccatgctggagataggaaccagcctcctctctcagactgcagag cagaccagaaagctgacagatgttgagacccaggtactaaatcaaacttctcgacttgag atacagctgctggagaattcattatccacctacaagctagagaagcaacttcttcaacag acaaatgaaatcttgaagatccatgaaaaaaacagtttattagaacataaaatcttagaa atggaaggaaaacacaaggaagagttggacaccttaaaggaagagaaagagaaccttcaa ggcttggttactcgtcaaacatatataatccaggagctggaaaagcaattaaacagagct accaccaacaacagtgtccttcagaagcagcaactggagctgatggacacagtccacaac cttgtcaatctttgcactaaagaaggtgttttactaaagggaggaaaaagagaggaagag aaaccatttagagactgtgcagatgtatatcaagctggttttaataaaagtggaatctac actatttatattaataatatgccagaacccaaaaaggtgttttgcaatatggatgtcaat gggggaggttggactgtaatacaacatcgtgaagatggaagtctagatttccaaagaggc tggaaggaatataaaatgggttttggaaatccctccggtgaatattggctggggaatgag tttatttttgccattaccagtcagaggcagtacatgctaagaattgagttaatggactgg gaagggaaccgagcctattcacagtatgacagattccacataggaaatgaaaagcaaaac tataggttgtatttaaaaggtcacactgggacagcaggaaaacagagcagcctgatctta cacggtgctgatttcagcactaaagatgctgataatgacaactgtatgtgcaaatgtgcc ctcatgttaacaggaggatggtggtttgatgcttgtggcccctccaatctaaatggaatg ttctatactgcgggacaaaaccatggaaaactgaatgggataaagtggcactacttcaaa gggcccagttactccttacgttccacaactatgatgattcgacctttagatttttga |
Protein Sequence |
>284 : length: 498 MTVFLSFAFLAAILTHIGCSNQRRSPENSGRRYNRIQHGQCAYTFILPEHDGNCRESTTD QYNTNALQRDAPHVEPDFSSQKLQHLEHVMENYTQWLQKLENYIVENMKSEMAQIQQNAV QNHTATMLEIGTSLLSQTAEQTRKLTDVETQVLNQTSRLEIQLLENSLSTYKLEKQLLQQ TNEILKIHEKNSLLEHKILEMEGKHKEELDTLKEEKENLQGLVTRQTYIIQELEKQLNRA TTNNSVLQKQQLELMDTVHNLVNLCTKEGVLLKGGKREEEKPFRDCADVYQAGFNKSGIY TIYINNMPEPKKVFCNMDVNGGGWTVIQHREDGSLDFQRGWKEYKMGFGNPSGEYWLGNE FIFAITSQRQYMLRIELMDWEGNRAYSQYDRFHIGNEKQNYRLYLKGHTGTAGKQSSLIL HGADFSTKDADNDNCMCKCALMLTGGWWFDACGPSNLNGMFYTAGQNHGKLNGIKWHYFK GPSYSLRSTTMMIRPLDF |