Pulmonary Arterial Hypertension KnowledgeBase (PAHKB)
PAHKB
Pulmonary Arterial Hypertension KnowledgeBase
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

3115

Name

HLA-DPB1

Synonym

DPB1|HLA-DP|HLA-DP1B|HLA-DPB;major histocompatibility complex, class II, DP beta 1;HLA-DPB1;major histocompatibility complex, class II, DP beta 1

Definition

HLA DP14-beta chain|HLA class II histocompatibility antigen, DP beta 1 chain|HLA class II histocompatibility antigen, DP(W4) beta chain|HLA-DP histocompatibility type, beta-1 subunit|MHC HLA DPB1|MHC class II HLA-DP-beta|MHC class II HLA-DP-beta-1|MHC cla

Position

6p21.3

Gene Type

protein-coding

PAH Type

Description

PAH

Association of clinical features with HLA in chronic pulmonary thromboembolism.

PAH

HLA-DPB1 and NFKBIL1 may confer the susceptibility to chronic thromboembolic pulmonary hypertension in the absence of deep vein thrombosis.
More detail of all Human literatures about HLA-DPB1

Pathways and Diseases

Pathway

Antigen processing and presentation;KEGG PATHWAY;hsa04612

Pathway

Type I diabetes mellitus;KEGG PATHWAY;hsa04940

Pathway

Allograft rejection;KEGG PATHWAY;hsa05330

Pathway

Asthma;KEGG PATHWAY;hsa05310

Pathway

Viral myocarditis;KEGG PATHWAY;hsa05416

Pathway

Staphylococcus aureus infection;KEGG PATHWAY;hsa05150

Pathway

Signaling in Immune system;Reactome;REACT:6900

Pathway

Systemic lupus erythematosus;KEGG PATHWAY;hsa05322

Pathway

Cell adhesion molecules (CAMs);KEGG PATHWAY;hsa04514

Pathway

Graft-versus-host disease;KEGG PATHWAY;hsa05332

Pathway

Leishmaniasis;KEGG PATHWAY;hsa05140

Pathway

Toxoplasmosis;KEGG PATHWAY;hsa05145

Pathway

Phagosome;KEGG PATHWAY;hsa04145

Pathway

Autoimmune thyroid disease;KEGG PATHWAY;hsa05320

Pathway

Intestinal immune network for IgA production;KEGG PATHWAY;hsa04672

Disease

atopy;GAD

Disease

leukemia, myeloid;GAD

Disease

pulmonary hypertension;GAD

Disease

graft-versus-host disease;GAD

Disease

thrombosis, deep vein;GAD

Disease

Polyarthritis;FunDO

Disease

multiple sclerosis;GAD

Disease

hepatitis B;GAD

Disease

Circulatory system diseases;KEGG DISEASE

Disease

Mycosis fungoides;FunDO

Disease

nephropathy in other diseases;GAD

Disease

endometriosis;GAD

Disease

silicosis;GAD

Disease

Leukemia;FunDO

Disease

pathological myopia;GAD

Disease

Asthma;GAD

Disease

asthma, aspirin-intolerant;GAD

Disease

Cardiac diseases;KEGG DISEASE

Disease

INFECTION;GAD

Disease

pulmonary thromboembolism;GAD

Disease

Hepatitis B;NHGRI

Disease

METABOLIC;GAD

Disease

Diabetes mellitus;FunDO

Disease

diabetes, type 1;GAD

Disease

bone marrow transplant;GAD

Disease

Celiac Disease;GAD

Disease

CARDIOVASCULAR;GAD

Disease

CANCER;GAD

Disease

Dilated cardiomyopathy (DCM);KEGG DISEASE;H00294

Disease

IMMUNE;GAD

Disease

REPRODUCTION;GAD

Disease

Urticaria;GAD

Disease

leukemia, acute lymphoblastic;GAD

Disease

Beryllium disease, chronic, susceptibility to;OMIM

Disease

cardiomyopathy;GAD

Disease

primary biliary cirrhosis;GAD

Disease

VISION;GAD

Disease

RENAL;GAD

External Links

Links to Entrez Gene

3115

Links to all GeneRIF Items

3115

Links to iHOP

3115

Sequence Information

Nucleotide Sequence

>3115 : length: 777
atgatggttctgcaggtttctgcggccccccggacagtggctctgacggcgttactgatg
gtgctgctcacatctgtggtccagggcagggccactccagagaattaccttttccaggga
cggcaggaatgctacgcgtttaatgggacacagcgcttcctggagagatacatctacaac
cgggaggagttcgcgcgcttcgacagcgacgtgggggagttccgggcggtgacggagctg
gggcggcctgctgcggagtactggaacagccagaaggacatcctggaggagaagcgggca
gtgccggacaggatgtgcagacacaactacgagctgggcgggcccatgaccctgcagcgc
cgagtccagcctagggtgaatgtttccccctccaagaaggggcccttgcagcaccacaac
ctgcttgtctgccacgtgacggatttctacccaggcagcattcaagtccgatggttcctg
aatggacaggaggaaacagctggggtcgtgtccaccaacctgatccgtaatggagactgg
accttccagatcctggtgatgctggaaatgaccccccagcagggagatgtctacacctgc
caagtggagcacaccagcctggatagtcctgtcaccgtggagtggaaggcacagtctgat
tctgcccggagtaagacattgacgggagctgggggcttcgtgctggggctcatcatctgt
ggagtgggcatcttcatgcacaggaggagcaagaaagttcaacgaggatctgcataa

Protein Sequence

>3115 : length: 258
MMVLQVSAAPRTVALTALLMVLLTSVVQGRATPENYLFQGRQECYAFNGTQRFLERYIYN
REEFARFDSDVGEFRAVTELGRPAAEYWNSQKDILEEKRAVPDRMCRHNYELGGPMTLQR
RVQPRVNVSPSKKGPLQHHNLLVCHVTDFYPGSIQVRWFLNGQEETAGVVSTNLIRNGDW
TFQILVMLEMTPQQGDVYTCQVEHTSLDSPVTVEWKAQSDSARSKTLTGAGGFVLGLIIC
GVGIFMHRRSKKVQRGSA



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