Pulmonary Arterial Hypertension KnowledgeBase (PAHKB)
PAHKB
Pulmonary Arterial Hypertension KnowledgeBase
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

3598

Name

IL13RA2

Synonym

CD213A2|CT19|IL-13R|IL13BP;interleukin 13 receptor, alpha 2;IL13RA2;interleukin 13 receptor, alpha 2

Definition

IL-13 receptor subunit alpha-2|IL-13R subunit alpha-2|IL-13R-alpha-2|IL-13RA2|cancer/testis antigen 19|interleukin 13 binding protein|interleukin 13 receptor alpha 2 chain|interleukin-13 receptor subunit alpha-2|interleukin-13-binding protein

Position

Xq13.1-q28

Gene Type

protein-coding

PAH Type

Description

PAH

Dysregulation of the IL-13 receptor system: a novel pathomechanism in pulmonary arterial hypertension.

PAH

IL-13 contributes to the development of pulmonary hypertension via an IL-13receptor alpha2-arginase 2-dependent pathway.
More detail of all Rat literatures about IL13RA2

Pathways and Diseases

Pathway

Interleukin signaling pathway;PANTHER;P00036

Pathway

Jak-STAT signaling pathway;KEGG PATHWAY;hsa04630

Pathway

IL4-mediated signaling events;PID Curated;200018

Disease

Cancer;FunDO

Disease

sclerosis, systemic;GAD

Disease

Systemic scleroderma;FunDO

Disease

IMMUNE;GAD

External Links

Links to Entrez Gene

3598

Links to all GeneRIF Items

3598

Links to iHOP

3598

Sequence Information

Nucleotide Sequence

>3598 : length: 1143
atggctttcgtttgcttggctatcggatgcttatatacctttctgataagcacaacattt
ggctgtacttcatcttcagacaccgagataaaagttaaccctcctcaggattttgagata
gtggatcccggatacttaggttatctctatttgcaatggcaacccccactgtctctggat
cattttaaggaatgcacagtggaatatgaactaaaataccgaaacattggtagtgaaaca
tggaagaccatcattactaagaatctacattacaaagatgggtttgatcttaacaagggc
attgaagcgaagatacacacgcttttaccatggcaatgcacaaatggatcagaagttcaa
agttcctgggcagaaactacttattggatatcaccacaaggaattccagaaactaaagtt
caggatatggattgcgtatattacaattggcaatatttactctgttcttggaaacctggc
ataggtgtacttcttgataccaattacaacttgttttactggtatgagggcttggatcat
gcattacagtgtgttgattacatcaaggctgatggacaaaatataggatgcagatttccc
tatttggaggcatcagactataaagatttctatatttgtgttaatggatcatcagagaac
aagcctatcagatccagttatttcacttttcagcttcaaaatatagttaaacctttgccg
ccagtctatcttacttttactcgggagagttcatgtgaaattaagctgaaatggagcata
cctttgggacctattccagcaaggtgttttgattatgaaattgagatcagagaagatgat
actaccttggtgactgctacagttgaaaatgaaacatacaccttgaaaacaacaaatgaa
acccgacaattatgctttgtagtaagaagcaaagtgaatatttattgctcagatgacgga
atttggagtgagtggagtgataaacaatgctgggaaggtgaagacctatcgaagaaaact
ttgctacgtttctggctaccatttggtttcatcttaatattagttatatttgtaaccggt
ctgcttttgcgtaagccaaacacctacccaaaaatgattccagaatttttctgtgataca
tga

Protein Sequence

>3598 : length: 380
MAFVCLAIGCLYTFLISTTFGCTSSSDTEIKVNPPQDFEIVDPGYLGYLYLQWQPPLSLD
HFKECTVEYELKYRNIGSETWKTIITKNLHYKDGFDLNKGIEAKIHTLLPWQCTNGSEVQ
SSWAETTYWISPQGIPETKVQDMDCVYYNWQYLLCSWKPGIGVLLDTNYNLFYWYEGLDH
ALQCVDYIKADGQNIGCRFPYLEASDYKDFYICVNGSSENKPIRSSYFTFQLQNIVKPLP
PVYLTFTRESSCEIKLKWSIPLGPIPARCFDYEIEIREDDTTLVTATVENETYTLKTTNE
TRQLCFVVRSKVNIYCSDDGIWSEWSDKQCWEGEDLSKKTLLRFWLPFGFILILVIFVTG
LLLRKPNTYPKMIPEFFCDT



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